Red blood cell distribution width to albumin ratio is correlated with prognosis of patients in coronary care unit  

作　　者：Jiao-Ni Wang Ze-Song Hu Yong-Wei Yu Xiao-Hui Peng 

机构地区：[1]Department of Diagnostic Ultrasound and Echocardiography,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou 310003,Zhejiang Province,China [2]Department of Cardiology,The Second Affiliated and Yuying Children’s Hospital of Wenzhou Medical University,Wenzhou 312500,Zhejiang Province,China [3]Intensive Care Unit,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,Zhejiang Province,China

出　　处：《World Journal of Cardiology》2025年第2期61-70,共10页世界心脏病学杂志(英文)

摘　　要：BACKGROUND As red blood cell distribution width(RDW)and albumin have been shown to be independent predictors of mortality from various diseases,this study aimed to investigate the effect of the RDW to albumin ratio(RA)as an independent predictor of the prognosis of patients admitted to the coronary care unit(CCU).AIM To use the RDW and albumin level to predict the prognosis of patients in the CCU.METHODS Data were obtained from the Medical Information Mart Intensive Care III database.The primary outcome was 365-day all-cause mortality,whereas the secondary outcomes were 30-and 90-day all-cause mortality,hospital length of stay(LOS),and CCU LOS.Cox proportional hazards regression model,propen-sity score matching,and receiver operating characteristic curve analyses were used.RESULTS The hazard ratio(95%confidence interval)of the upper tertile(RA>4.66)was 1.62(1.29 to 2.03)when compared with the reference(RA<3.84)in 365-day all-cause mortality.This trend persisted after adjusting for demographic and clinical variables in the propensity score-matching analysis.Similar trends were observed for the secondary outcomes of hospital and CCU LOS.Receiver operating characteristic curve analysis was performed by combining the RA and sequential organ failure assessment(SOFA)scores,and the C-statistic was higher than that of the SOFA scores(0.733 vs 0.702,P<0.001).CONCLUSION RA is an independent prognostic factor in patients admitted to the CCU.RA combined with the SOFA score can improve the predictive ability of the SOFA score.However,our results should be verified in future prospective studies.

关 键 词：Red blood cell distribution width ALBUMIN PROGNOSIS Coronary care unit 

分 类 号：R54[医药卫生—心血管疾病]