Left bundle branch pacing cardiac resynchronization therapy vs biventricular pacing cardiac resynchronization therapy–time to write a requiem for biventricular pacing-cardiac resynchronization therapy  

作　　者：Akshyaya Pradhan Daljeet Saggu Monika Bhandari 

机构地区：[1]Department of Cardiology,King George's Medical University,Lucknow 226003,Uttar Pradesh,India [2]Department of Cardiac Electrophysiology,AIG Hospitals,Hyderabad 500034,Telangāna,India

出　　处：《World Journal of Cardiology》2025年第2期118-124,共7页世界心脏病学杂志(英文)

摘　　要：Cardiac resynchronization therapy(CRT)reduces heart failure(HF)hospitaliz-ations and all-cause mortality in patients with HF with reduced ejection fraction with left bundle branch(LBB)block.Biventricular pacing(BVP)is considered the gold standard for achieving CRT;however,approximately 30%–40%of patients do not respond to BVP-CRT.Recent studies have demonstrated that LBB pacing(LBBP)produces remarkable results in CRT.In this meta-analysis,LBBP-CRT showed better outcomes than conventional BVP-CRT,including greater QRS duration reduction and left ventricular ejection fraction improvement,along with consistently lower pacing thresholds on follow-up.Additionally,there was a grea-ter reduction in New York Heart Association class and brain natriuretic peptide levels.This study contributes to the growing body of encouraging data on LBBP-CRT from recent years.With ongoing technological advancements and increasing operator expertise,the day may not be far when LBBP-CRT becomes the standard of care rather than the exception.

关 键 词：Heart failure Left bundle branch block area pacing Narrow QRS New York Heart Association class Left ventricular ejection fraction 

分 类 号：R654.2[医药卫生—外科学]