血清降钙素原、中性粒细胞/淋巴细胞比值、血小板/淋巴细胞比值与急性胰腺炎患者病情严重程度的相关性  

Correlation between serum procalcitonin,neutrophil/lymphocyte ratio,platelet/lymphocyte ratio and severity of acute pancreatitis

作　　者：李存刚 李新生 LI Cungang;LI Xinsheng(Department of Clinical Laboratory of Yuanyang County People’s Hospital,Xinxiang 453500 Henan,China)

机构地区：[1]原阳县人民医院医学检验科,河南新乡453500

出　　处：《中国民康医学》2025年第4期148-150,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:分析血清降钙素原(PCT)、血小板/淋巴细胞比值(PLR)、中性粒细胞/淋巴细胞比值(NLR)与急性胰腺炎患者病情严重程度的相关性。方法:回顾性分析2020年3月至2023年3月该院收治的85例急性胰腺炎患者的临床资料,设为急性胰腺炎组,根据病情严重程度将其分为轻度患者(n=35)、中度患者(n=33)、重度患者(n=17),另选取同期80名健康体检者,设为对照组。比较两组和不同病情严重程度患者的血清PCT、PLR、NLR水平、急性生理学及慢性健康状况评分系统Ⅱ(APACHEⅡ)评分,血清PCT、PLR、NLR水平与急性胰腺炎患者病情严重程度的相关性采用Pearson相关性分析。结果:急性胰腺炎组血清PCT、PLR、NLR水平均高于对照组,差异有统计学意义(P<0.05);重度患者血清PCT、PLR、NLR水平均高于中度患者和轻度患者,且中度患者高于轻度患者,差异有统计学意义(P<0.05);重度患者APACHEⅡ评分均高于中度患者和轻度患者,且中度患者高于轻度患者,差异有统计学意义(P<0.05);Pearson相关性分析结果显示,血清PCT、PLR、NLR水平与急性胰腺炎患者病情严重程度均呈正相关(r>0,P<0.05)。结论:血清PCT、PLR、NLR水平与急性胰腺炎患者病情严重程度均呈正相关。Objective:To analyze correlation between serum procalcitonin(PCT),platelet/lymphocyte ratio(PLR),neutrophil/lymphocyte ratio(NLR)and severity of acute pancreatitis.Methods:The clinical data of 85 patients with acute pancreatitis admitted to this hospital from March 2020 to March 2023 were retrospectively analyzed and they were set as acute pancreatitis group.According to the severity of the disease,they were divided into mild patients(n=35),moderate patients(n=33)and severe patients(n=17).In addition,80 healthy subjects were selected as the control group.The serum PCT,PLR,NLR levels and acute physiology and chronic health evaluation II(APACHE II)scores were compared between the two groups and among the patients with different disease severities.Pearson correlation was used to analyze the correlation between the serum PCT,PLR,NLR levels and the severity of the disease.Results:The levels of serum PCT,PLR and NLR in the acute pancreatitis group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of serum PCT,PLR and NLR in the severe patients with acute pancreatitis were higher than those in the moderate patients and the mild patients,those in the moderate patients were higher than those in the mild patients,and the differences were statistically significant(P<0.05).The APACHE II score of the severe patients was higher than those of the moderate patients and the mild patients,that of moderate patients was higher than that of mild patients,and the differences were statistically significant(P<0.05).Pearson correlation analysis showed that serum PCT,PLR and NLR levels were positively correlated with the severity of acute pancreatitis(r>0,P<0.05).Conclusions:The serum PCT,PLR and NLR levels are positively correlated with the severity of acute pancreatitis.

关 键 词：急性胰腺炎 血小板 淋巴细胞 中性粒细胞 相关性 

分 类 号：R587.2[医药卫生—内分泌]