曲安奈德联合平阳霉素治疗微囊型淋巴管畸形的疗效分析  

Analysis of the therapeutic effect of combination therapy with triamcinolone acetonide and pingyangmycin on microcystic lymphatic malformations

作　　者：皮梦奇 赵磊[1] 徐伟洋 徐淼 丁语[1] PI Mengqi;ZHAO Lei;XU Weiyang;XU Miao;DING Yu(Department of Interventional Hemangioma&Vascular Surgery,Children's Hospital Affiliated to Zhengzhou University,Zhengzhou 450018,China)

机构地区：[1]郑州大学附属儿童医院介入血管瘤&血管外科,河南省郑州市450018

出　　处：《组织工程与重建外科》2025年第1期36-39,共4页Journal of Tissue Engineering and Reconstructive Surgery

摘　　要：目的探讨曲安奈德联合平阳霉素治疗微囊型淋巴管畸形的疗效。方法2022年3月至2024年3月,48例微囊型淋巴管畸形患儿分为两组:曲安奈德联合平阳霉素治疗组(实验组)和单纯平阳霉素治疗组(对照组),比较两组患儿分别治疗1次、2次、3次后的治愈率及并发症发生率。结果实验组治疗1次、2次、3次后的治愈率分别为32.00%、60.00%、92.00%,对照组分别为4.35%、30.43%、60.87%。两组3次治疗后的治愈率均明显高于1次治疗后(P<0.001),每次治疗后实验组治愈率均高于对照组(P<0.05)。实验组并发症发生率(12.00%)低于对照组(39.13%),差异具有统计学意义(P<0.05)。结论曲安奈德联合平阳霉素治疗微囊型淋巴管畸形能提高治愈率并减少并发症发生率,可作为一种更优的临床治疗选择。Objective To explore the therapeutic effect of triamcinolone acetonide combined with pingyangmycin in the treatment of microcystic lymphatic malformations.Methods From March 2022 to March 2024,48 children with microcystic lymphangioma were divided into two groups,namely the experimental group treated with combination of triamcinolone acetonide and pingyangmycin and the control group treated with pingyangmycin alone.The cure rate after 1,2 and 3 treatments and complication rate of the two groups were compared.Results The cure rate of the experimental group after 1,2,and 3 treatments were 32.00%,60.00%,and 92.00%,respectively,while those of the control group were 4.35%,30.43%,and 60.87%,respectively.The cure rate of the two groups after 3 treatments was significantly higher than that after 1 treatment(P<0.001);After each treatment,the cure rate of the experimental group was higher than that of the control group(P<0.05).The complication rate of the experimental group(12.00%)was lower than that of the control group(39.13%),and the difference was statistically significant(P<0.05).Conclusion The combination of triamcinolone acetonide and pingyangmycin in the treatment of microcystic lymphatic malformations can improve the cure rate and reduce the incidence of complications,and can be a better clinical treatment option.

关 键 词：曲安奈德 平阳霉素 淋巴管畸形 微囊型 硬化治疗 

分 类 号：R551.2[医药卫生—血液循环系统疾病]