多肽微阵列芯片制备技术与应用进展  

Progress in Peptide Microarray Preparation Techniques and Applications

作　　者：罗日朗 祝丽芬 李绍元[1] 席风硕 于洁[1] 马文会[1,3] LUO Rilang;ZHU Lifen;LI Shaoyuan;XI Fengshuo;YU Jie;MA Wenhui(Faculty of Metallurgical and Energy Engineering,Kunming University of Science and Technology,Kunming 650093,China;Anesthesiology Department,Kunming First People s Hospital,Kunming 650034,China;School of Engineering,Yunnan University,Kunming 650500,China)

机构地区：[1]昆明理工大学冶金与能源工程学院,云南昆明650093 [2]昆明市第一人民医院麻醉科,云南昆明650034 [3]云南大学现代工学院,云南昆明650500

出　　处：《昆明理工大学学报(自然科学版)》2025年第1期132-145,共14页Journal of Kunming University of Science and Technology(Natural Science)

基　　金：国家自然科学基金项目(52274408,52204314);云南省优秀青年基金项目(202201AW070014).

摘　　要：多肽微阵列芯片作为一种新兴的生物信息分析工具,展现出广阔的应用前景.全面梳理多肽微阵列芯片的制备技术与应用进展,有助于挖掘和实现其潜在价值.首先追踪了多肽微阵列芯片制备技术的发展历程,并对不同的制备技术进行了比较分析;回顾了多肽微阵列芯片在生物医学研究中的应用,并探讨了其应用潜力.尽管多肽微阵列芯片技术取得了显著进展,但仍有必要进一步深化研究;并展望了多肽微阵列芯片技术的未来发展趋势,旨在为科研工作提供有价值的参考和启示.As an emerging bioinformatics analysis tool,the peptide microarray chip has demonstrated a broad application prospect.A comprehensive review of the fabrication techniques and application progress of peptide microarray chips can help to explore and realize their potential value.This article first traces the development history of peptide microarray chip fabrication techniques and compares different fabrication methods.It then reviews the application of peptide microarray chips in biomedical science research and discusses their potential applications in research.Although significant progress has been made in peptide microarray chip technology,further in-depth research is still necessary.Moreover,the article looks forward to the future development trends of peptide microarray chip technology,aiming to provide valuable references and insights for research in the field.

关 键 词：多肽微阵列芯片 生物芯片 蛋白质组学 生物信息分析 

分 类 号：TN40[电子电信—微电子学与固体电子学] Q811.4[生物学—生物工程]