基于微纳技术的铂类药物检测研究进展  

Research progress on platinum-based drug detection based on micro-nano technology

作　　者：杨雨倩 黄小凤 青琳森[2] 梁健[2] 谢静 Yang Yuqian;Huang Xiaofeng;Qing Linsen;Liang Jian;Xie Jing(Key Laboratory of Structure-Specific Small Molecule Drugs of Chengdu Medical College in Sichuan Province,Chengdu 610500,China;Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu 610213,China)

机构地区：[1]成都医学院药学院结构特异性小分子药物研究四川省高等学校重点实验室,成都610500 [2]中国科学院成都生物研究所,成都610213

出　　处：《分析仪器》2025年第1期1-8,共8页Analytical Instrumentation

基　　金：四川省科技计划(2022YFS0011)。

摘　　要：高效、准确、低消耗地检测铂类药物对于癌症治疗和保障人民的生命健康具有重大意义。近年来,随着材料科学、电化学和微型化技术的发展,微流控技术和纳米材料在铂类药物检测中的新应用逐渐增加。不少研究者们通过对微流控技术和纳米材料的合理应用,设计出了多种技术方法用于铂类药物的检测当中。与传统的铂类药物检测技术相比之下,微纳技术优势突出,具有高通量、高精准度、低消耗等优点。本文对微纳技术检测铂类药物的应用进行了全面综述,以期为铂类药物的检测提供研究思路,促进微纳技术在铂类药物检测中的发展,提高对癌症的治疗和控制能力。Efficient,accurate and low consumption detection of platinum drugs is of great significance for cancer treatment and safeguarding people's lives and health.In recent years,with the development of materials science,electrochemistry and miniaturization technology,the new applications of microfluidic technology and nanomaterials in the detection of platinum drugs have gradually increased.Through the rational application of microfluidic technology and nanomaterials,many researchers have designed a variety of technical methods for the detection of platinum drugs.Compared with the traditional platinum drug detection technology,micro and nano technology has outstanding advantages,such as high throughput,high accuracy,low consumption and other advantages.In this paper,the application of micro-nano technology in the detection of platinum drugs is comprehensively reviewed,in order to provide research ideas for the detection of platinum drugs,promote the development of micro-nano technology in the detection of platinum drugs,and improve the treatment and control ability of cancer.

关 键 词：铂类 微流控 纳米 芯片 检测 

分 类 号：TQ460.72[医药卫生—药物分析学]