2018-2022年晋江市HIV感染者/艾滋病患者生存时间及其影响因素分析  

Analysis of the survival time and its influencing factors among HIV-infected/AIDS patients in Jinjiang City,2018-2022

作　　者：林巧莉 许名源 许毓颖 LIN Qiaoli;XU Mingyuan;XU Yuying(Jinjiang Municipal Hospital(Shanghai Sixth People's Hospital Fujian Campus),Jinjiang,Fujian 362200,China;Jinjiang Center for Disease Control and Prevention)

机构地区：[1]晋江市医院(上海市第六人民医院福建医院),福建晋江362200 [2]晋江市疾病预防控制中心

出　　处：《华南预防医学》2024年第12期1120-1123,1129,共5页South China Journal of Preventive Medicine

摘　　要：目的 了解2018-2022年晋江市HIV感染者/艾滋病患者生存时间及其影响因素。方法 通过中国疾病预防控制信息系统艾滋病综合防治信息系统收集2018-2022年晋江市HIV感染者/艾滋病患者的病例资料,使用单、多因素Cox比例风险回归模型分析HIV感染者/艾滋病患者生存时间的影响因素。结果 2018-2022年登记现住址为晋江市的HIV感染者/艾滋病患者共937例,男性774例,女性163例。截至观察终点,937例报告病例中,艾滋病相关死亡151例,艾滋病相关病死率为16.12%,平均生存时间为154.55个月(95%CI:138.20~170.90)。多因素Cox比例风险模型结果显示,基线CD4+T淋巴细胞200~<350个/μL(HR=0.21,95%CI:0.10~0.43)、≥350个/μL(HR=0.18,95%CI:0.09~0.37)、接受ART(HR=0.07,95%CI:0.04~0.13)死亡风险较低。结论 基线CD4+T淋巴细胞水平以及ART是HIV感染者/艾滋病患者生存的影响因素。Objective To analyze the survival time of HIV-infected/AIDS patients and its influencing factors in Jinjiang City from 2018 to 2022.Methods The case data of HIV-infected/AIDS patients in Jinjiang City from 2018 to 2022 were derived from the“AIDS Comprehensive Prevention and Control Data Information Management System”of China Disease Prevention and Control Information System,and the influencing factors of the survival time of HIV-infected/AIDS patients were analyzed using univariate and multivariate Cox proportional risk regression models.Results From 2018 to 2022,a total of 937 HIV-infected/AIDS patients with current addresses in Jinjiang City were registered,including 774 males and 163 females.At the end of observation,151 of the 937 reported cases were AIDS-related deaths,the AIDS-related fatality rate was 16.12%,and the mean survival time was 154.55 months(95%CI:138.20-170.90).Multivariate Cox proportional risk model results showed that baseline CD4+T lymphocytes were 200-<350/μL(HR=0.21,95%CI:0.10-0.43),≥350/μL(HR=0.18,95%CI:0.09-0.37),and antiviral therapy(ART)(HR=0.07,95%CI:0.04-0.13)had a lower risk of death.Conclusion Baseline CD4+T lymphocyte levels and ART are factors influencing survival in HIV-infected/AIDS patients.

关 键 词：HIV感染者/艾滋病患者 抗病毒治疗 生存时间 影响因素 

分 类 号：R183.9[医药卫生—流行病学]