布地奈德福莫特罗粉吸入剂联合八段锦治疗尘肺病临床观察  

Efficacy Analysis the Budesonide Formoterol Powder Inhalation Combined with Baduanjin in the Treatment of Pneumoconiosis

作　　者：王海舰 赵汉毅 杨宝江[3] 李奇阳 张亚男 马桂琴(指导)[5] WANG Haijian;ZHAO Hanyi;YANG Baojiang;LI Qiyang;ZHANG Ya'nan;MA Guiqin(Department of Traditional Chinese Medicine,Beijing Institute of Chemical Industry Occupational Disease Prevention and Treatment/Beijing Institute of Occupational Disease Prevention and Treatment,Beijing 100093,China;Department of Geriatrics,General Hospital of Beijing Jingmei Group;Department of Pulmonary Disease,Fangshan Hospital of Beijing University of Chinese Medicine,Beijing 102300,China;Department of Acupuncture and Moxibustion,Shijingshan District Hospital of Traditional Chinese Medicine,Beijing 102300,China;Department of Rheumatology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 102300,China)

机构地区：[1]北京市化工职业病防治院/北京市职业病防治研究院中医科,北京100093 [2]北京京煤集团总医院老年科,北京102300 [3]北京中医药大学房山医院肺病科,北京102300 [4]北京市石景山区中医医院针灸科,北京102300 [5]中国中医科学院广安门医院风湿病科,北京102300

出　　处：《光明中医》2025年第2期343-346,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：北京市石景山区名中医传承工作室建设项目(No.石卫健中医发[2020]5号)。

摘　　要：目的探讨布地奈德福莫特罗粉吸入剂联合八段锦治疗尘肺病的临床疗效。方法选取2022年1月—2024年3月在北京市化工职业病防治院及京煤集团总医院就诊的77例确诊尘肺病患者作为观察对象,分为对照组(38例)和观察组(39例)。对照组使用布地奈德福莫特罗粉吸入剂治疗,观察组在对照组的基础上联合八段锦干预。2组分别于治疗前、治疗3个月、治疗6个月采用肺功能指标[用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、第1秒用力呼气容积与用力肺活量比值(FEV1/FVC)]及6 min步行距离评估临床疗效及不良反应。结果与治疗前相比,2组患者肺功能、6 min步行距离等各项指标均有改善,差异有统计学意义(P<0.05),且观察组肺功能、6 min步行距离改善情况均优于对照组,差异有统计学意义(P<0.05)。对照组1例患者出现不良反应,观察组2例患者出现不良反应。结论布地奈德福莫特罗粉吸入剂联合八段锦治疗尘肺病能明显改善患者的肺功能、增强运动耐力,且安全性良好。Objective To explore the clinical efficacy of Budipine formoterol powder inhalation combined with Baduanjin in the treatment of pneumoconiosis.Methods Seventy-seven patients diagnosed with pneumoconiosis who visited our hospital and General Hospital of Jingmei Group from January 2022 to March 2024 were selected as subjects and divided into a control group(38 cases)and an observation group(39 cases).The control group was treated with Budipine formoterol powder inhalation,while the observation group received Baduanjin intervention on the basis of the control group.Both groups were evaluated for clinical efficacy and adverse reactions using pulmonary function indicators,includes forced vital capacity(FVC),forced expiratory volume in one second(FEV_1),and the ratio of FEV_1 to FVC(FEV_1/FVC)and 6-minute walking distance before treatment,after 3 months of treatment,and after 6 months of treatment.Results Compared with before treatment,pulmonary function,6-min walking distance and other indexes of the two groups were improved,and the difference was statistically significant(P<0.05).The improvement of lung function and 6 min walking distance in the observation group was better than that in the control group,and the difference was statistically significant(P<0.05).Adverse reactions occurred in 1 patient in the control group and 2 patients in the observation group.Conclusion Budipine formoterol powder inhalation combined with Baduanjin in the treatment of pneumoconiosis can significantly improve the lung function and enhance exercise endurance,with good safety.

关 键 词：肺痹 尘肺病 布地奈德福莫特罗粉吸入剂 八段锦 中西医结合疗法 

分 类 号：R13[医药卫生—劳动卫生]