基于脑肠轴理论观察朱氏头皮针对卒中后抑郁患者情绪及胃肠功能的影响  

Effects of Zhu′s scalp acupuncture on mood and gastrointestinal function in post-stroke depression patients based on the theory of brain-gut axis

作　　者：黄瑞雪 潘宾[1] 唐婷 胡晓雅 王晓敬 Huang Ruixue;Pan Bin;Tang Ting;Hu Xiaoya;Wang Xiaojing(The First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei Anhui 230031;Anhui University of Chinese Medicine,Hefei Anhui 230038)

机构地区：[1]安徽中医药大学第一附属医院,安徽合肥230031 [2]安徽中医药大学,安徽合肥230038

出　　处：《山西中医药大学学报》2025年第2期175-180,共6页Journal of Shanxi University of Chinese Medicine

基　　金：安徽省高校自然科学重点项目(KJ2021A0605)。

摘　　要：目的:基于脑肠轴理论观察朱氏头皮针对卒中后抑郁(PSD)患者情绪及胃肠功能的影响。方法:将63例PSD伴胃肠道症状的患者根据随机原则分为朱氏头皮针组和常规针刺组,中途脱落3例。最终入组60例,每组各30例,两组均给予降低颅内压、抗凝等常规治疗。常规针刺组患者采用常规穴位针刺治疗,主穴选取百会、内关、三阴交、极泉、尺泽、委中,辅以配穴曲池、合谷、阳陵泉、足三里、膈俞、心俞、膻中、太冲、中脘,1次/d,6次/周,连续治疗4周。朱氏头皮针组在常规针刺组的基础上给予头皮针治疗,取头面区、巅顶区、上焦区、下焦区,留针时间4~8 h,1次/2 d,连续治疗4周。观察两组患者治疗前后汉密尔顿抑郁量表(HAMD-24)、美国国立卫生研究院卒中量表(NIHSS)、胃肠道症状评定量表(GSRS)评分变化,并比较两组的临床疗效。结果:两组患者治疗后HAMD-24、NIHSS、GSRS评分均较治疗前降低,差异均有统计学意义(P<0.05)。朱氏头皮针组患者治疗后HAMD-24、NIHSS、GSRS评分均低于常规针刺组,治疗前后HAMD-24、NIHSS、GSRS评分差值均高于常规针刺组,差异有统计学意义(P<0.01)。两组患者基于HAMD-24评分的有效率比较及基于GSRS评分的有效率比较,差异均有统计学意义(P<0.01)。结论:朱氏头皮针通过针刺调节神经、内分泌、脾胃及肠道实现脑-肠同治,对于PSD患者在改善情绪及缓解胃肠功能症状方面具有一定的疗效。Objective:To observe the effect of Zhu′s scalp acupuncture on mood and gastrointestinal function in patients with post-stroke depression(PSD)based on the theory of brain-gut axis.Methods:63 PSD patients with gastrointestinal symptoms were randomly divided into a Zhu′s scalp acupuncture group(32 cases)and a conventional acupuncture group(31 cases).Patients in the conventional acupuncture group were treated with conventional acupuncture at Baihui,Neiguan,Sanyinjiao,Jiquan,Chize and Weizhong acupoints,assisted by acupoints of Quchi,Hegu,Yanglingquan,Zusanli,Geshu,Xinshu,Danzhong,Taichong and Zhongwan,once a day,6 times a week for 4 weeks.On the basis of the treatment in the conventional acupuncture group,the patients in the Zhu′s scalp acupuncture group were treated with scalp acupuncture at the head-face area,top-head area,upper energizer area and lower energizer area.The needles were retained for 4~8 hours,once every 2 days for 4 weeks.Before and after treatment,the scores of Hamilton Depression Scale(HAMD-24),National Institutes of Health Stroke Scale(NIHSS)and Gastrointestinal Symptom Rating Scale(GSRS)were observed in the two groups,and the clinical efficacy was compared between the two groups.Results:The HAMD-24,NIHSS and GSRS scores of the two groups after treatment were significantly lower than those before treatment,and the differences were statistically significant(P<0.05).After treatment,the HAMD-24,NIHSS and GSRS scores of the Zhu′s scalp acupuncture group were lower than those of the conventional acupuncture group,and the differences of HAMD-24,NIHSS and GSRS scores before and after treatment in the Zhu′s scalp acupuncture group were higher than those in the conventional acupuncture group,with the statistical significance(P<0.01).There were statistically significant differences in the effective rate based on HAMD-24 score and the effective rate based on GSRS score between the two groups(P<0.01).Conclusion:Zhu′s scalp acupuncture can regulate the nerve,endocrine,spleen,stomach and intestinal

关 键 词：卒中后抑郁 朱氏头皮针 胃肠道症状 汉密尔顿抑郁量表 胃肠道症状评定量表 

分 类 号：R246.7[医药卫生—针灸推拿学] R255.2[医药卫生—中医临床基础] R743.3[医药卫生—中医学] R749.9