Surgical Ablation in Congenital Heart Disease:Advances in Techniques and Clinical Outcomes  

作　　者：Manouk H.C.Linderhof Hoang H.Nguyen Annemien E.van den Bosch Mathijs S.van Schie Vehpi Yildirim Yannick J.H.J.Taverne Natasja M.S.de Groot 

机构地区：[1]Department of Cardiology,Erasmus Medical Center,Rotterdam,3015GD,The Netherlands [2]Department of Cardiology,UT Southwestern Medical Center,Dallas,TX 75390,USA [3]Department of Cardiothoracic Surgery,Erasmus Medical Center,Rotterdam,3015GD,The Netherlands

出　　处：《Congenital Heart Disease》2024年第6期577-592,共16页先天性心脏病(英文)

基　　金：supported by funding grants from NWO-Vidi[grant number 91717339];Medical Delta and CIRCULAR NWO(NWA.1389.20.157)/NWO.

摘　　要：Surgical ablation(SA)has become an essential rhythm-control strategy for managing tachyarrhythmias in patients with congenital heart disease.Atrial tachyarrhythmias,such as atrial flutter and atrial fibrillation,are prevalent in congenital heart disease,affecting up to 50%of patients,and pose significant risks,including increased morbidity and mortality.Ventricular tachyarrhythmias,though less common,can lead to sudden cardiac death,particularly in conditions like Tetralogy of Fallot.Prior studies suggested that SA for tachyarrhythmias in patients with congenital heart disease offers significant benefits,including superior long-term rhythm control compared to catheter ablation(CA).Atrial tachyarrhythmia burden is effectively reduced by SA,such as the Cox-Maze IVprocedure,thereby also improving the quality of life.Ablation strategies targeting critical isthmuses in the ventricles,such as between the tricuspid valve annulus and right ventricular outflow tract scar in patients with Tetralogy of Fallot,are effective in managing ventricular tachyarrhythmias.However,SA is associated with procedural risks,such as sinus node dysfunction and atrioventricular conduction block.Despite these risks,SA is recommended for congenital heart disease patients with symptomatic tachyarrhythmias unresponsive to drug therapy and CA,and it is increasingly considered as a prophylactic procedure in high-risk patients.Emerging innovative technologies,including enhanced mapping-and hybrid ablation techniques,are poised to further improve SA outcomes.The goal of this review is to assess the efficacy,outcomes,and risks of SA in congenital heart disease patients,compare the outcomes of SA with CA,and evaluate the risk-benefit ratio of(prophylactic)arrhythmia surgery.In summary,SA offers significant benefits,including longterm arrhythmia control and improved quality of life,particularly in patients in whom CA is unfeasible or has failed.Although SA is currently underutilized in clinical practice,the potential as a comprehensive treatment for sp

关 键 词：Surgical ablation congenital heart disease ARRHYTHMIAS 

分 类 号：R54[医药卫生—心血管疾病]