中药复方治疗缺血性脑卒中研究进展  

Advancements in Treating Ischemic Stroke with Chinese Medicine Compounds Formulae

作　　者：刘文杰 高圆圆 白雪 LIU Wenjie;GAO Yuanyuan;BAI Xue(Experimental Research Center,China Academy of Chinese Medical Sciences,Beijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment of Major Disease,Beijing 100700,China;The First Clinical Medical College,Henan University of ChineseMedicine,Zhengzhou Henan 450046,China)

机构地区：[1]中国中医科学院医学实验中心,北京市中医药防治重大疾病基础研究重点实验室,北京100700 [2]河南中医药大学第一临床医学院,河南郑州450046

出　　处：《中国药物警戒》2024年第12期1382-1387,共6页Chinese Journal of Pharmacovigilance

基　　金：国家自然科学基金资助项目(82304767);中央级公益性科研院所基本科研业务费专项基金(JJPY2022021、ZZ15-YQ-055);中国中医科学院科技创新工程项目(CI2021B017);中国中医科学院西苑医院院级师承项目(YJMPSC202437)。

摘　　要：目的综述中药复方在治疗缺血性脑卒中的相关研究,为开展更多中药复方治疗缺血性脑卒中临床与实验研究提供参考。方法通过检索从建库至2024年10月20日中国知网、PubMed数据库,对治疗缺血性脑卒中的相关中药复方进行归纳和分析。结果临床表明补阳还五汤、星蒌承气汤、桃红四物汤等中药复方在临床上治疗缺血性脑卒中有较好疗效。结论中药复方在治疗缺血性脑卒中方面具有一定的优势,但研究相对薄弱、临床研究和大规模试验方面存在不足,缺乏多样本、高质量的临床试验,需加大研究力度。Objective To examine findings related to the applications of TCM compound formulae in the management of ischemic stroke,and to offer data for subsequent clinical and experimental investigations.Methods By searching China Knowledge Network and PubMed for articles published from the inception to October 20,2024,TCM compound formulae were summarized and evaluated.Results Clinical investigations indicated that TCM compound formulae,including Buyang Huanwu Tang,Xinglou Chengqi Tang,and Taohong Siwu Tang,exhibited substantial therapeutic efficacy in patients with ischemic stroke.Conclusion TCM compound formulae possess considerable benefits in the management of ischemic stroke.However,investigations are comparatively limited,and there is a lack of clinical studies and large-scale trials.Multi-sample and high-quality clinical studies are lacking.

关 键 词：中药复方 缺血性脑卒中 补阳还五汤 星蒌承气汤 桃红四物汤 灯盏生脉胶囊 血府逐瘀汤 

分 类 号：R994.11[医药卫生—毒理学] R743[医药卫生—药学]