经鼻高流量湿化氧疗与无创正压通气治疗急性加重期慢性阻塞性肺疾病合并Ⅰ型呼吸衰竭的疗效比较  

Comparison of Efficacy of High-flow Nasal Cannula Oxygen Therapy and Non-invasive Positive Pressure Ventilation in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated with TypeⅠRespiratory Failure

作　　者：李密 熊新军 何雪珂 LI Mi;XIONG Xinjun;HE Xueke(Department of Internal MedicineⅠ,Jingshan Renhe Hospital,Jingshan 431800,Hubei,China;Department of Neurology,Jingshan Renhe Hospital,Jingshan 431800,Hubei,China)

机构地区：[1]京山仁和医院内一科,湖北京山431800 [2]京山仁和医院神经内科,湖北京山431800

出　　处：《世界复合医学(中英文)》2024年第10期23-26,共4页World Journal of Complex Medicine

摘　　要：目的 评估经鼻高流量湿化氧疗、无创正压通气应用在急性加重期慢性阻塞性肺疾病合并Ⅰ型呼吸衰竭患者中的效果。方法 将2020年1月—2022年12月于京山仁和医院进行诊治的60例急性加重期慢性阻塞性肺疾病合并Ⅰ型呼吸衰竭患者,以不同的治疗方法分组,对照组(30例,给予无创正压通气治疗)和观察组(30例,给予经鼻高流量湿化氧疗治疗)。比较两组治疗后的不同结局。结果 观察组治疗总有效率更高,差异有统计学意义(P<0.05)。在并发症总发生率[3.33%(1/30)vs20.00%(6/30)]方面,观察组更低,差异有统计学意义(χ^(2)=4.043,P<0.05)。治疗后,在血气参数方面,差异无统计学意义(P均>0.05)。结论 急性加重期慢性阻塞性肺疾病合并Ⅰ型呼吸衰竭患者实施经鼻高流量湿化氧疗的临床效果较好、并发症发生率较低。Objective To evaluate the effect of high-flow nasal cannula oxygen therapy and non-invasive positive pressure ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease complicated with typeⅠrespiratory failure.Methods Sixty patients with acute exacerbation of chronic obstructive pulmonary disease complicated with typeⅠrespiratory failure who were treated at Jingshan Renhe Hospital from January 2020 to December 2022 were divided into two groups using different treatment methods:a control group(30 cases,treated with non-invasive positive pressure ventilation) and an observation group(30 cases,treated with nasal high flow humidified oxygen therapy).Compared the different outcomes of two groups after treatment.Results The total effective rate of the observation group was higher,and the difference was statistically significant(P<0.05).Ⅰn terms of the overall incidence of complications [3.33%(1/30) vs 20.00%(6/30)],the observation group had a lower incidence,and the difference was statistically significant(χ~2=4.043,P<0.05).After treatment,there was no statistically significant difference in blood gas parameters(both P>0.05).Conclusion The clinical effect of nasal high flow humidified oxygen therapy is better and the incidence of complications is lower in patients with acute exacerbation of chronic obstructive pulmonary disease complicated with type Ⅰ respiratory failure.

关 键 词：慢性阻塞性肺疾病 经鼻高流量湿化氧疗 无创正压通气 

分 类 号：R563[医药卫生—呼吸系统]