乙醇中毒急诊治疗的临床效果分析  

Clinical Effect of Emergency Treatment of Ethanol Poisoning

作　　者：彭斌 吕庄 方忠琪 PENG Bin;LYU Zhuang;FANG Zhongqi(Department of Emergency,Universal Medical Xidian Group Hospital,Xi'an 710077,Shaanxi,China;Department of Internal Medicinev,Bo'ao Evergrande International Hospital,Qionghai 571437,Hainan,China;Bo'ao Yiling Life Care Center,Qionghai 571437,Hainan,China)

机构地区：[1]环球医疗西电集团医院急诊科,陕西西安710077 [2]博鳌恒大国际医院内五科,海南琼海571437 [3]博鳌一龄生命养护中心,海南琼海571437

出　　处：《世界复合医学(中英文)》2024年第10期35-38,共4页World Journal of Complex Medicine

摘　　要：目的 分析乙醇中毒急诊治疗的临床效果。方法 选择2023年1—12月环球医疗西电集团医院收治的300例乙醇中毒患者,按照不同的治疗方法分为两组。两组患者入院后均进行常规治疗和处理,对照组(150例)应用纳洛酮治疗,观察组(150例)在对照组基础上应用丹参注射液治疗。比较两组临床指标、氧化因子指标、肝功能指标及不良反应发生情况。结果 与对照组比较,观察组呼吸恢复时间、意识恢复时间和肌力恢复时间均更短,差异有统计学意义(P均<0.05)。治疗后,与对照组比较,观察组丙二醛、谷胱甘肽过氧化物酶、超氧化物歧化酶、谷丙转氨酶、谷草转氨酶水平均更优,差异有统计学意义(P均<0.05)。观察组不良反应发生率为6.67%(10/150),低于对照组的19.33%(29/150),差异有统计学意义(χ^(2)=10.640,P<0.05)。结论 在乙醇中毒急诊治疗中联合应用纳洛酮和丹参注射液,效果较为理想。Objective To analyze the clinical effect of emergency treatment of ethanol poisoning.Methods From January to December 2023,300 patients with ethanol poisoning admitted to the Global Medical Xidian Group Hospital were selected and divided into two groups according to different treatment methods.The patients in the two groups were treated with routine treatment and treatment after admission.The control group(150 cases) was treated with naloxone,and the observation group(150 cases) was treated with Danshen injection on the basis of the control group.The clinical indexes,oxidative factor indexes,liver function indexes and adverse reactions were compared between the two groups.Results Compared with the control group,the respiratory recovery time,consciousness recovery time and muscle strength recovery time in the observation group were shorter,and the differences were statistically significant(all P<0.05).After treatment,compared with the control group,the levels of malondialdehyde,glutathione peroxidase,superoxide dismutase,alanine aminotransferase and aspartate aminotransferase in the observation group were better,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the observation group was 6.67%(10/150),which was lower than 19.33%(29/150) in the control group,and the difference was statistically significant(χ~2=10.640,P<0.05).Conclusion The effect of naloxone combined with Danshen Injection in the emergency treatment of ethanol poisoning is ideal.

关 键 词：乙醇中毒 急诊治疗 纳洛酮 丹参注射液 

分 类 号：R4[医药卫生—临床医学]