蒲地蓝消炎口服液联合帕拉米韦治疗流行性感冒病毒感染的疗效及安全性研究  

Study on the Efficacy and Safety of Pudilan Anti-inflammatory Oral Solution Combined with Peramivir in Influenza Virus Infection

作　　者：殷鸾鸾 顾红琴 YIN Luanluan;GU Hongqin(Department of Internal Medicine,Jiangdu Maternal and Child Health Hospital,Yangzhou 225200,Jiangsu,China)

机构地区：[1]扬州市江都妇幼保健院内科,江苏扬州225200

出　　处：《世界复合医学(中英文)》2024年第10期48-51,共4页World Journal of Complex Medicine

摘　　要：目的 分析蒲地蓝消炎口服液与帕拉米韦在流行性感冒病毒感染中的作用。方法 选取2020年3月—2023年8月扬州市江都妇幼保健院收治的95例流行性感冒患者为研究对象,按照治疗方法不同将患者分为两组。对照组(n=47)采用帕拉米韦治疗,研究组(n=48)在对照组基础上结合蒲地蓝消炎口服液治疗。对比两组临床疗效、炎性因子水平、不良反应发生率。结果 研究组治疗有效率为100.00%(48/48),高于对照组的87.23%(41/47),差异有统计学意义(P=0.033)。治疗后,研究组C反应蛋白、白细胞介素-8、白细胞介素-6水平均低于对照组,差异有统计学意义(P均<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 蒲地蓝消炎口服液联合帕拉米韦治疗流行性感冒,能够提高临床疗效、降低炎症反应,且安全性较高。Objective To analyze the role of Pudilan Anti-inflammatory Oral Solution and peramivir in influenza virus infection.Methods A total of 95 patients with influenza admitted to Yangzhou Jiangdu Maternal and Child Health Hospital from March 2020 to August 2023 were selected as the research objects,and the patients were divided into two groups according to different treatment methods.The control group(n=47) was treated with peramivir,and the study group(n=48) was treated with Pudilan Anti-inflammatory Oral Solution on the basis of the control group.The clinical efficacy,inflammatory factor levels and incidence of adverse reactions were compared between the two groups.Results The effective rate of treatment in the study group was 100.00%(48/48),which was higher than 87.23%(41/47) in the control group,and the difference was statistically significant(P=0.033).After treatment,the levels of C-reactive protein,interleukin-8 and interleukin-6 in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Pudilan Anti-inflammatory Oral Solution combined with peramivir in the treatment of influenza can improve the clinical efficacy,reduce the inflammatory response,and has high safety.

关 键 词：蒲地蓝消炎口服液 帕拉米韦 流行性感冒病毒 不良反应 炎性因子 

分 类 号：R246.1[医药卫生—针灸推拿学]