酸枣仁汤加味联合穴位贴敷治疗对围绝经期失眠患者中医证候积分和睡眠症状的影响  

Effects of modified Suanzaoren Decoction combined with acupoint application treatment on the scores of traditional Chinese medicine syndromes and sleep symptoms in patients with perimenopausal insomnia

作　　者：孙晨 林椠 张健 SUN Chen;LIN Qian;ZHANG Jian(Department of Traditional Chinese Medicine,Kailuan General Hospital,Tangshan 063001,Hebei,China;Department of Traditional Chinese Medicine,Tangshan Maternal and Child Health Hospital,Tangshan 063003,Hebei,China)

机构地区：[1]开滦总医院中医科,河北唐山063001 [2]唐山市妇幼保健院中医科,河北唐山063003

出　　处：《中国性科学》2025年第2期116-119,共4页Chinese Journal of Human Sexuality

基　　金：河北省2023年度中医药类科学研究课题计划项目(2023209)。

摘　　要：目的探讨酸枣仁汤加味联合穴位贴敷治疗对围绝经期失眠患者中医证候积分和睡眠症状的影响。方法选取2022年1月至2024年1月开滦总医院收治的206例围绝经期失眠患者作为研究对象,按照随机数字表法分为西医组和中医组,每组103例。西医组采用常规西医治疗,中医组采用酸枣仁汤加味联合穴位贴敷治疗。比较两组临床疗效、治疗前后中医证候积分、匹兹堡睡眠质量指数(PSQI)评分、不良反应发生率。结果治疗4周后,中医组治疗有效率高于西医组(P<0.05)。治疗4周后,两组失眠、多梦、心悸、焦虑评分均低于治疗前,且中医组均低于西医组(P<0.05)。治疗4周后,两组主观睡眠质量、入睡时间、睡眠时间、睡眠效率评分均低于治疗前,且中医组均低于西医组(P<0.05)。治疗4周后,中医组不良反应发生率低于西医组(P<0.05)。结论酸枣仁汤加味联合穴位贴敷治疗围绝经期失眠患者能够提高临床疗效,改善症状,提高睡眠质量,减少不良反应发生。Objective To explore the effects of modified Suanzaoren Decoction combined with acupoint application treatment on the scores of traditional Chinese medicine(TCM)syndromes and sleep symptoms in patients with perimenopausal insomnia.Methods A total of 206 patients with perimenopausal insomnia admitted in Kailuan General Hospital between January 2022 and January 2024 were enrolled as research objects.According to random number table method,they were divided into Western medicine group and TCM group,with 103 cases in each group.The Western medicine group was treated with conventional Western medicine treatment,and the TCM group used modified Suanzaoren decoction combined with acupoint application treatment.The clinical curative effect,scores of TCM syndromes and Pittsburgh sleep quality index(PSQI)before and after treatment,and incidence of adverse reactions were compared between the two groups.Results After 4 weeks of treatment,the response rate of treatment in the TCM group was higher than that in the Western medicine group(P<0.05).After 4 weeks of treatment,the scores of insomnia,dreaminess,palpitation,and anxiety were lower than those before treatment in both groups,and those in the TCM group were lower than those in the Western medicine group(P<0.05).After 4 weeks of treatment,the scores of subjective sleep quality,falling asleep time,sleep time and sleep efficiency in both groups were lower than before treatment,and those in the TCM group were lower than those in the Western medicine group(P<0.05).After 4 weeks of treatment,the incidence of adverse reactions in the TCM group was lower than that in the Western medicine group(P<0.05).Conclusions Modified Suanzaoren Decoction combined with acupoint application can improve clinical curative effect,syndromes and sleep quality,and reduce adverse reactions in treating patients with perimenopausal insomnia.

关 键 词：酸枣仁汤加味 穴位贴敷 小剂量雌激素 围绝经期失眠 

分 类 号：R271[医药卫生—中医妇科学]