应用营养诊疗流程模型对非小细胞肺癌患者生存质量的临床研究  

Clinical Study on the Impact of an Applied Nutrition Care Process and Model on the Quality of Life in Patients with Non-Small Cell Lung Cancer

作　　者：杨洋[1] 宫琛 李倩[1] 郝吉庆[3] YANG Yang;GONG Chen;LI Qian;HAO Jiqing(Department of Oncology Ward 2,Suzhou Hospital of Anhui Medical University,Suzhou,Anhui 234000,China;Central Laboratory,Suzhou Hospital of Anhui Medical University,Suzhou,Anhui 234000,China;Department of Oncology,The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230000,China)

机构地区：[1]安徽医科大学附属宿州医院肿瘤内科二病区,安徽宿州234000 [2]安徽医科大学附属宿州医院中心实验室,安徽宿州234000 [3]安徽医科大学附属第一医院肿瘤内科,安徽合肥230000

出　　处：《临床肺科杂志》2025年第3期407-411,421,共6页Journal of Clinical Pulmonary Medicine

基　　金：安徽省卫生健康科研项目(AHWJ2023A30205);宿州市卫生健康科研重点项目(SZWJ2023a001)。

摘　　要：目的评价应用营养诊疗流程模型(NCPM)对非小细胞肺癌(NSCLC)患者营养状况、负性情绪以及生存质量的影响。方法选取2021年12月至2023年11月安徽医科大学附属宿州医院收治的91例患者,随机分为研究组(47例)和对照组(44例),化疗期间研究组采用NCPM干预,对照组不予以营养干预。对比治疗前后两组患者体质量指数(BMI)、肱三头肌皮褶厚度(TSF)、上臂肌围(AMC)、血红蛋白(Hb)、血清总蛋白(TP)、血清白蛋白(ALB)、负性情绪[焦虑自评量表(SAS)、抑郁自评量表(SDS)]及生存质量量表评定(EORTC QLQ-C30)。结果治疗后,研究组BMI、Hb水平及EORTC QLQ-C30量表中社会功能、躯体功能维度评分较治疗前升高,SAS评分、SDS评分较治疗前降低(P<0.05),对照组TSF、AMC、TP、ALB水平及SDS评分较治疗前降低(P<0.05);且治疗后研究组与对照组比较,TSF、AMC、TP、ALB水平及EORTC QLQ-C30量表中社会功能、心理功能维度评分高,SAS评分、SDS评分低(P<0.05)。治疗期间,两组胃肠道反应发生率比较差异无统计学意义(P>0.05)。结论采用NCPM干预能提高NSCLC患者的营养状况,减轻负性情绪,改善生存质量。Objective To evaluate the effects of the nutrition care process and model(NCPM)on nutritional status,negative emotions and quality of life in patients with non-small cell lung cancer(NSCLC).Methods A total of 91 patients admitted to Suzhou Hospital of Anhui Medical University from December 2021 to November 2023 were randomly divided into a study group(47 cases)and a control group(44 cases).During chemotherapy,the study group received NCPM intervention,while the control group received no nutritional intervention.Body mass index(BMI),triceps skin fold thickness(TSF),upper arm muscle circumference(AMC),hemoglobin(Hb),serum total protein(TP),serum albumin(ALB),negative mood[Self-rating Anxiety Scale(SAS),self-rating Depression Scale(SDS)]and quality of life[European organization for research and treatment of cancer quality of life questionnaire-core 30(EORTC QLQ-C30)]were compared between the two groups before and after treatment.Results After treatment,the levels of BMI,TSF,Hb,and EORTC QLQ-C30 social and physical functions were higher than before treatment,while SAS and SDS were lower than before treatment(P<0.05).The levels of TSF,AMC,TP,ALB,and SDS in the control group were lower than those before treatment(P<0.05).After treatment,compared with the control group,TSF,AMC,TP,ALB,and EORTC QLQ-C30 social function and psychological function scores were higher in the study group and lower in the SAS score and SDS score(P<0.05).During treatment,there was no significant difference in the incidence of gastrointestinal reactions between the two groups(P>0.05).Conclusion NCPM intervention can improve the nutritional status of NSCLC patients,alleviate negative emotions,and improve the quality of life.

关 键 词：营养诊疗流程模型 营养干预 非小细胞肺癌 营养状况 情绪 生存质量 

分 类 号：R47[医药卫生—护理学]