稀土镁合金在骨科中的最新研究进展  

Latest research progress of rare earth-magnesium alloys in orthopedics

作　　者：孙正明[1,2] 左坤 朱新科 岳浩 高正超 SUN Zhengming;ZUO Kun;ZHU Xinke;YUE Hao;GAO Zhengchao(Department of Orthopedics,Shaanxi Provincial People's Hospital,Xi'an 710068,China;Key Laboratory of Basic and Clinical Transformation of Bone and Joint Diseases in Shaanxi Province,Xi'an 710068,China;Department of Orthopedics,Yangxian Traditional Chinese Medicine Hospital,Yangxian 723300,China)

机构地区：[1]陕西省人民医院骨科,陕西西安710068 [2]陕西省骨关节疾病基础与临床转化重点实验室,陕西西安710068 [3]陕西省洋县中医医院骨科,陕西洋县723300

出　　处：《南方医科大学学报》2025年第2期437-442,共6页Journal of Southern Medical University

基　　金：国家自然基金青年科学基金(82101453);陕西省科技创新团队(2024RS-CXTD-60);陕西省人民医院科技发展孵化基金项目(2021YJY-42)。

摘　　要：因镁合金具有良好的弹性模量、可降解和促进骨修复等性能成为了骨科内植物材料的研究热点。目前,大多数生物镁合金因降解过快不能满足骨科需求,稀土镁合金具有良好的耐腐蚀性等性能,有望成为临床骨科内植物的重要材料。本文就稀土的生理作用、对镁合金性能的影响,稀土镁合金体外生物相容性、动物体内生物相容性、对腱骨愈合的影响及临床骨科应用现状等研究进展进行综述。Due to their good properties of elastic modulus,degradability and ability to promote bone repair,magnesium alloys have become a research hotspot in research of orthopedic implants.Nevertheless,most of the biomedical magnesium alloys currently available fail to meet the requirements in orthopedics because of their rapid degradation after implantation.Rare earth-magnesium alloys possess excellent corrosion resistance and are expected to become important materials as clinical orthopedic implants.This review summarizes the recent progress in studies of the physiological functions of rare earth elements,the effects of supplementation of rare earth elements on biomechanical properties and the in vitro and in vivo biocompatibility of magnesium alloys,and their contribution to tendon-bone healing,addressing also the current clinical orthopedic applications of different rare earth-magnesium alloys,challenges,and future strategies for improving these alloys.

关 键 词：稀土镁合金 生物相容性 耐腐蚀性 

分 类 号：TG1[金属学及工艺—金属学]