特发性突聋与心血管系统及精神神经系统的关联性  

Associations idiopathic sudden deafness and cardiovascular system and psychoneurotic system

作　　者：方延青 徐江红[1] 陈兵[1] 舒易来[1] FANG Yanqing;XU Jianghong;CHEN Bing;SHU Yilai(Fudan University Affiliated Eye&ENT Hospital,Key Laboratory of Auditory Medicine,National Health Commission,Shanghai 200031,China)

机构地区：[1]复旦大学附属眼耳鼻喉科医院,国家卫生健康委员会听觉医学重点实验室,上海200031

出　　处：《中国耳鼻咽喉颅底外科杂志》2025年第1期100-105,110,共7页Chinese Journal of Otorhinolaryngology-skull Base Surgery

基　　金：上海科学技术委员会-生物医药处-创新计划(23Y11909700)。

摘　　要：特发性突聋(即特发性突发性感音神经性耳聋,以下简称“突聋”)病因不明,可能原因为病毒感染、血管、免疫、代谢及遗传因素等。尽管对突聋病因的探究持续不断,但目前仍无确切结论。既往研究多基于个体临床检验报告等相对微观层面,随着病例资料电子化与集成化,大数据分析技术极大地助力了疾病相关的科研工作。得益于此,以英文发表的相关研究也越来越多地聚焦于宏观层面,即利用基于人群数据库进行突聋与其他疾病之间的关联性研究,有助于从多层面、多维度对突聋病因进行归纳和调研,但结果尚有出入,也未见相关综述,不利于直接览读。因此,本文主要从大数据角度,针对突聋与心血管系统及精神神经系统疾病的关联性进行文献综述。It is unknown for the etiology of idiopathic sudden deafness(i.e.idiopathic sudden sensorineural deafness,hereinafter referred to as“sudden deafness”for short).The possible causes include viral infection,vascular,immune,metabolic and genetic factors.Although the etiology of sudden deafness is investigated continuously,there is still no definite conclusion.Previous studies were mostly based on the relatively micro-examination levels of individual clinical reports.With the electronization and integration of patient data,the analysis technology of big data has also greatly assisted disease-related scientific research.Benefitting from the technology,relevant studies published in English have increasingly focused on the correlation between sudden deafness and other diseases based on population databases on the macro level.The study is helpful to summarize and investigate the causes of sudden deafness from multiple levels and multiple aspects.However,the results are still inconsistent.And there is no relevant review,which is not conducive to the read directly.Therefore,this paper mainly reviews the literature on the relationship between sudden deafness and cardiovascular system and psycho-nervous system diseases from the perspective of big data.

关 键 词：突发性耳聋 队列研究 心血管系统 精神神经系统 

分 类 号：R764.437[医药卫生—耳鼻咽喉科]