血管炎症在主动脉夹层发病机制中的研究进展  

Research progress on vascular inflammation in the pathogenesis of aortic dissection

作　　者：李妍洁 向紫萍 刘欣 张明明[3] LI Yanjie;XIANG Ziping;LIU Xin;ZHANG Mingming(Graduate School of North China University of Technology,Tangshan,Hebei 063000,China;Graduate School of Hebei Medical University,Shijiazhuang,Hebei 050000,China;Clinical Medical Research Center of Hebei Provincial People's Hospital,Shijiazhuang,Hebei 050000,China)

机构地区：[1]华北理工大学研究生院,河北省唐山市063000 [2]河北医科大学研究生学院,河北省石家庄市050000 [3]河北省人民医院临床医学研究中心,河北省石家庄市050000

出　　处：《中国动脉硬化杂志》2025年第2期163-168,共6页Chinese Journal of Arteriosclerosis

基　　金：国家自然科学基金面上项目(82270508);河北省“三三三人才工程”资助项目(A202105015)。

摘　　要：目前,随着诊断新技术的发展,主动脉夹层的检出率逐年提高,但其死亡率仍居高不下。心血管疾病是一种慢性炎症性疾病,而血管炎症在主动脉夹层进展过程中起到了主要作用。为此,文章系统描述了炎症细胞、炎症因子以及炎性小体在主动脉夹层发展过程中的具体作用及机制。At present,with the development of new diagnostic technologies,the detection rate of aortic dissection has been increasing year by year,but its mortality rate still remains high.Cardiovascular disease is a chronic inflammatory disease,and vascular inflammation plays a major role in the progression of aortic dissection.Therefore,this article systematically describes the specific roles and mechanisms of inflammatory cells,inflammatory factors,and inflammasomes in the development of aortic dissection.

关 键 词：主动脉夹层 血管炎症 炎症细胞 炎症因子 炎性小体 

分 类 号：R5[医药卫生—内科学] R392[医药卫生—临床医学]