GC-NCI-MS法测定植物源性食品中氟虫腈及其3种代谢产物残留量  

Determination of Fipronil and Its Three Metabolites in Foods of Plant Origin by GC-NCI-MS

作　　者：肖舒元 邱硕 李艳洋 孙安琪 马嘉泽 刘朋宇 姜璇 XIAO Shuyuan;QIU Shuo;LI Yanyang;SUN Anqi;MA Jiaze;LIU Pengyu;JIANG Xuan(Shenyang Institute for Food and Drug Control,Shenyang 110136,China)

机构地区：[1]沈阳市食品药品检验所,辽宁沈阳110136

出　　处：《现代食品》2025年第1期164-168,174,共6页Modern Food

摘　　要：本文建立气相色谱-负化学源-质谱法(Gas Chromatography-Negative Ion Chemical Ionization-Mass Spectrometry,GC-NCI-MS)测定植物源性食品中氟虫腈及其3种代谢产物残留量的方法。以乙腈为提取溶剂,采用程序升温进样,在选择离子监测模式下进行测定,外标法定量。结果显示,氟虫腈及其3种代谢产物质量浓度在0.005~0.200μg·mL^(-1)线性关系良好,相关系数R^(2)≥0.9991,方法定量限为0.001 mg·kg^(-1);在0.002、0.010、0.020 mg·kg^(-1)的3个加标水平下,测定得到目标物质的回收率为80.6%~109.0%,相对标准偏差在2.1%~10.6%。该方法可为植物源性食品中氟虫腈及其3种代谢产物残留量的检测提供技术支持。A gas chromatography-negative chemical source-mass spectrometry(GC-NCI-MS)method was developed for the determination of residues of fipronil and its 3 metabolites in plant-derived foods.Acetonitrile was used as extraction solvent,temperature programmed injection was used,and the determination was carried out under selected ion monitoring mode.The results showed that there was a good linear relationship between fipronil and its three metabolites in the range of 0.005~0.200μg·mL^(-1) with correlation coefficient R^(2)≥0.9991.The limit of quantification was 0.001 mg·kg^(-1).The recoveries were 80.6%~109.0%and the relative standard deviations were 2.1%~10.6%at three additive levels of 0.002,0.010 and 0.020 mg·kg^(-1).This method can provide technical support for the detection of residues of fipronil and its 3 metabolites in plant-derived foods.

关 键 词：气相色谱-负化学源-质谱法(GC-NCI-MS) 植物源性食品 氟虫腈 代谢产物 

分 类 号：S481.8[农业科学—农药学]