普济痔疮栓对混合痔痔上黏膜套扎术后创面水肿及炎症状态的影响  

Effect of Inserting Traditional Chinese Medicine Suppositories into the Anus on Wound Edema and Inflammatory State After Ligation of the Superior Anal Mucosa in Patients with Mixed Hemorrhoids

作　　者：杨锋[1] 张胜威[1] 李晓洁[1] 杨会举[2] YANG Feng;ZHANG Shengwei;LI Xiaojie;YANG Huiju(Anorectal Surgery Department,the Fifth Clinical Medical College of Henan University of Traditional Chinese Medicine(Zhengzhou People′s Hospital);The Third Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450000 China)

机构地区：[1]河南中医药大学第五临床医学院(郑州人民医院)肛肠外科 [2]河南中医药大学第三附属医院肛肠病医院,河南郑州450000

出　　处：《锦州医科大学学报》2025年第1期75-80,共6页Journal of Jinzhou Medical University

基　　金：河南省中医药拔尖人才专项课题,项目编号:2022ZYBJ16。

摘　　要：目的观察中药栓剂纳肛对混合痔患者痔上黏膜套扎术后创面水肿及炎症状态的影响。方法选取自2022年2月至2024年1月在郑州人民医院接受治疗的需进行痔上黏膜套扎术的混合痔患者共计100例。为确保研究的科学性和公正性,采用随机数字表法将这100例患者随机分为两组,即对照组和观察组,每组各包含50例患者。对照组将接受常规的治疗方案,而观察组则在常规治疗基础上加入特定的干预措施,以便对比两组患者的治疗效果和康复情况。对照组除常规止血、抗生素治疗外,采用中药熏洗进行术后治疗,观察组在对照组基础上行中药栓剂纳肛治疗。观察两组手术指标及创面愈合时间,比较两组术后第1、7、14天创面水肿、肛门出血情况,比较两组炎症状态,记录两组术后6个月复发情况。结果两组在手术时间及出血量方面的差异无统计学意义(P>0.05),表明两组在这两个指标上的表现基本相当,没有明显的区别。但在创面愈合时间的对比中,观察组的表现明显优于对照组,其创面愈合时间明显更短,差异有统计学意义(P<0.05),显示出观察组在创面愈合方面的明显优势。术后第1天两组创面水肿分布情况差异有统计学意义(U=0.032,P=0.974),在术后第7天和第14天的观察期间,研究组中创面呈现I度水肿的患者数量分布明显多于对照组,此结果表明在相同的时间节点上,观察组患者的创面水肿程度较轻的比例明显高于对照组,显示出治疗措施在减轻术后水肿方面的积极效果,差异有统计学意义(U=2.139、2.158,P=0.032、0.031)。术后第1天两组肛门出血分布情况差异无统计学意义(U=0.036,P=0.971),术后第7、14天观察组肛门出血I度患者分布高于对照组,差异有统计学意义(U=2.005、2.068,P=0.045、0.039)。在术后第1天,两组患者的炎症状态经过统计学分析,结果显示差异无统计学意义(P>0.05),表明在此时间点上Objective To observe the effect of inserting traditional Chinese medicine suppositories into the anus on wound edema and inflammatory state after ligation of the superior anal mucosa in patients with mixed hemorrhoids.Methods A total of 100 patients with mixed hemorrhoids were selected from February 2022 to January 2024.In order to ensure the scientific and fair nature of the study,the 100 patients were randomly divided into two groups,namely the control group and the observation group,and each group contained 50 patients.The control group will receive the usual treatment regimen,while the observation group will add a specific intervention to the usual treatment to compare the treatment effect and rehabilitation of the two groups.In addition to conventional hemostasis and antibiotic therapy,the control group used traditional Chinese medicine fumigation for postoperative treatment,and the observation group was treated in the control group.The surgical index and wound healing time of the two groups were observed,compared the wound edema and anal bleeding on days 1,day 17 and day 14 after the surgery,compared the inflammatory status of the two groups,and recorded the recurrence at 6 months after the operation.Results There was no significant difference in the operation time and the amount of blood loss between the two groups(P>0.05),indicating that the performance of the two groups in the two indicators was basically comparable,with no obvious difference.However,in the comparison of wound healing time,the observation group performed significantly better than the control group,and the wound healing time was significantly shorter,statistically significant(P<0.05),showing the obvious advantage of the observation group in wound healing.The distribution of wound edema between the two groups(U=0.032,P=0.974).During the observation period on days 7 and 14 after the operation,the number of patients in the study group was significantly higher than the wound edema in the control group,showing the positive effect of treatment

关 键 词：混合痔 痔上黏膜套扎术 中药栓剂 纳肛 创面水肿 炎症状态 

分 类 号：R657.18[医药卫生—外科学]