中老年男性体格测量、体成分与定量CT腰椎骨密度相关性  

The correlation between physical measurements,body composition analysis and lumbar bone density in middle-aged and elderly men based on quantitative CT

作　　者：刘澳 周菁 孙永兵 戚昕 杜亚玮 周阳 李中林[5] 武肖玲 邹智 吕雪[7] 李永丽[2] 李昊 LIU Ao;ZHOU Jing;SUN Yongbing;QI Xin;DU Yawei;ZHOU Yang;LI Zhonglin;WU Xiaoling;ZOU Zhi;LYU Xue;LI Yongli;LI Hao(Department of Medical Imaging,Zhengzhou University People’s Hospital,Zhengzhou 450003,China;Department of Health Management,Henan Provincial People’s Hospital,Key Laboratory of Chronic Disease Health Management of Henan Province,Zhengzhou 450003,China;Xinxiang Medical University,Xinxiang 453000,China;Department of Medical Imaging,Henan University People’s Hospital,Zhengzhou 450003,China;Department of Medical Imaging,Henan Provincial People’s Hospital,Zhengzhou 450003,China;Department of Nuclear Medicine,Henan Provincial People’s Hospital,Zhengzhou 450003,China;Henan Provincial People’s Hospital,Zhengzhou 450003,China;Fuwai Central China Cardiovascular Hospital,Zhengzhou 451464,China)

机构地区：[1]郑州大学人民医院医学影像科,河南郑州450003 [2]河南省人民医院健康管理学科,河南省慢病健康管理重点实验室,河南郑州450003 [3]新乡医学院,河南郑州450003 [4]河南大学人民医院医学影像科,河南郑州450003 [5]河南省人民医院医学影像科,河南郑州450003 [6]河南省人民医院核医学科,河南郑州450003 [7]河南省人民医院,河南郑州450003 [8]阜外华中心血管病医院,河南郑州451464

出　　处：《中国骨质疏松杂志》2025年第2期204-209,共6页Chinese Journal of Osteoporosis

基　　金：国家自然科学基金项目(82071884);国家重点研发计划(2022YFC2010000,2022YFC2010001);中原科技创新领军人才计划(244200510016);河南省医学科技计划项目(SBGJ202302011);河南省科技攻关计划项目(242102311121,242102311018,242102310299)。

摘　　要：目的应用定量CT(quantitative computed tomography,QCT)技术测量腰椎骨密度(bone mineral density,BMD),探讨体格测量、体成分分析指标与中老年男性腰椎BMD的相关性。方法本研究为横断面研究,选取2018年1月至2023年2月在河南省人民医院健康管理中心接受体格检查的1152名中老年男性体检者为研究对象,采集受试者年龄、身高、体重、血压、腰围、臀围、体脂肪质量与体肌肉质量数据,并计算体质量指数(body mass index,BMI)、体脂率(body fat percentage,BFP)与骨骼肌质量指数(skeletal muscle mass index,SMI)。同时使用QCT技术测量受试者腰椎BMD值,按照BMI进行分组,分为BMI正常组(18.5≤BMI<24 kg/m^(2))、超重及肥胖组(BMI为>24 kg/m^(2)),并在两组中分别按照骨量诊断标准进行讨论。采用单因素方差分析,Pearson相关性分析和偏相关分析体格测量、体成分分析指标与腰椎BMD的相关性。结果在BMI正常组中,骨质疏松组的年龄、收缩压、腰臀比、BFP显著高于骨量正常组,SMI显著低于骨量正常组与骨量减少组(P均<0.05);超重及肥胖组中,骨质疏松组的年龄、收缩压、腰围、腰臀比与BFP显著高于骨量正常组,SMI显著低于骨量正常组与骨量减少组(P均<0.05)。Pearson相关性分析结果显示,BMI正常组中腰椎BMD值与年龄、腰围、腰臀比、BFP呈显著负相关关系(r=-0.385,r=-0.122,r=-0.199,r=-0.168,P均<0.05),与SMI呈正相关(r=0.226,P<0.05);超重及肥胖组中腰椎BMD值与年龄、收缩压、腰围、腰臀比、BFP呈显著负相关关系(r=-0.379,r=-0.087,r=-0.101,r=-0.187,r=-0.199,P均<0.05),与SMI呈正相关(r=0.251,P<0.05)。在校正年龄因素后,偏相关分析分析结果显示,BMI正常组中腰椎BMD值与腰围、腰臀比、BFP呈显著负相关关系(r=-0.157,r=-0.212,r=-0.134,P均<0.05),与SMI呈正相关(r=0.167,P<0.05);超重及肥胖组中腰椎BMD值与腰围、腰臀比、BFP呈显著负相关关系(r=-0.120,r=-0.163,r=-0.126,P均<0.05),�Objective To explore the correlation between physical measurement,body composition analysis indexes and lumbar spine bone mineral density(BMD)in middle-aged and elderly male based on Quantitative CT(QCT).Methods This study is a cross-sectional study,1152 middle-aged and elderly male physical examination subjects who underwent physical examination at the Health Management Center of Henan Provincial People’s Hospital from January 2018 to February 2023 were selected as the study subjects,and the data of age,height,weight,blood pressure,waist circumference,hip circumference,body fat mass and body muscle mass were collected,and body mass index(BMI),body fat percentage(BFP)and skeletal muscle mass index(SMI),and the BMD value of the lumbar spine was measured by QCT technology,and the subjects were divided into normal BMI group(18.5≤BMI<24 kg/m^(2))and overweight and obesity group(BMI>24 kg/m^(2)),and the two groups were discussed according to the bone mass diagnostic criteria.One-way ANOVA,Pearson correlation analysis and partial correlation analysis were used to analyze the correlation between physical measures and body composition analysis and lumbar BMD.Results In the normal BMI group,the age,systolic blood pressure,waist-to-hip ratio and BFP of the osteoporosis group were significantly higher than those of the normal bone mass group,and the SMI was significantly lower than that of the normal bone mass group and the osteopenia group(all P<0.05).The result of Pearson correlation analysis showed that the BMD value of the lumbar spine was negatively correlated with age,waist circumference,waist-to-hip ratio and BFP in the normal BMI group(r=-0.385,r=-0.122,r=-0.199,r=-0.168,all P<0.05),and positively correlated with SMI(r=0.226,P<0.05),the BMD value of lumbar spine was significantly negatively correlated with age,systolic blood pressure,waist circumference,waist-hip ratio and BFP in the overweight and obese groups(r=-0.379,r=-0.087,r=-0.101,r=-0.187,r=-0.199,all P<0.05),and was positively correlated with SMI(r=0.25

关 键 词：QCT技术 腰椎BMD 体格测量 体成分分析 相关性分析 

分 类 号：R681[医药卫生—骨科学]