癌症化疗患者照顾者经济毒性的潜在剖面分析及与创伤后应激障碍的关系  

Latent profile analysis of financial toxicity among caregivers of cancer patients with chemotherapy and its relationship with post-traumatic stress disorder

作　　者：王海凤 方继红[1,3] 王利敏 于雪杰 Wang Haifeng;Fang Jihong;Wang Limin;Yu Xuejie(School of Nursing,Anhui Medical University,Hefei 230001,China;Department of Otorhinolaryngology,Head and Neck Surgery,the First Affiliated Hospital of University of Science and Technology of China,Hefei;Nursing Department,Anhui Provincial Children's Hospital,Hefei 230041,China)

机构地区：[1]安徽医科大学护理学院,合肥230001 [2]中国科学技术大学附属第一医院耳鼻咽喉头颈外科,合肥230001 [3]安徽省儿童医院护理部,合肥230041

出　　处：《中华现代护理杂志》2025年第6期771-778,共8页Chinese Journal of Modern Nursing

基　　金：2023安徽省卫健委科研项目(一般项目)(AHWJ2023A20371);2024年度安徽医科大学护理学院研究生青苗培育项目(hlqm12024102)。

摘　　要：目的了解癌症化疗患者照顾者经济毒性的潜在类别,分析各类别与创伤后应激障碍的关系。方法采用便利抽样法,选取2024年2—4月在中国科学技术大学附属第一医院南区肿瘤化疗科、日间化疗科和西区肿瘤化疗科进行治疗的256名癌症化疗患者照顾者为研究对象。采用一般资料调查表、癌症家庭照顾者经济毒性量表和事件影响量表-修订版对研究对象进行问卷调查。采用Mplus 8.0软件对经济毒性的潜在类别进行分析,采用有序Logistic回归分析癌症化疗患者照顾者经济毒性潜在类别的影响因素,采用多重线性回归分析经济毒性的潜在类别和创伤后应激障碍的关系。结果本研究共发放问卷256份,回收有效问卷242份,问卷有效回收率为94.53%(242/256)。242名癌症化疗患者照顾者经济毒性可分为3个潜在类别,包括低经济毒性-低行为改变组(9.92%)、中经济毒性-中应对潜力组(36.78%)和高经济毒性-高应对困难组(53.31%)。有序Logistic回归分析结果显示,工作状态、职业、文化程度是癌症化疗患者照顾者经济毒性潜在类别的影响因素(P<0.05)。与低经济毒性-低行为改变组的照顾者相比,中经济毒性-中应对潜力组和高经济毒性-高应对困难组的照顾者创伤后应激障碍更严重(P<0.01)。结论癌症化疗患者照顾者经济毒性可分为3种潜在类别,不同经济毒性类别的照顾者创伤后应激障碍水平存在差异,建议医护人员基于癌症化疗患者照顾者经济毒性同质群体来进行针对性管理,以缓解其创伤后应激障碍症状。ObjectiveTo explore the latent categories of financial toxicity among caregivers of cancer patients with chemotherapy and to analyze the relationship between each category and post-traumatic stress disorder(PTSD).MethodsConvenience sampling was used to select 256 cancer patients with chemotherapy in the Department of Oncology Chemotherapy and the Department of Daytime Chemotherapy in the South Zone,and the Department of Oncology Chemotherapy in the West Zone of the First Affiliated Hospital of University of Science and Technology of China from February to April 2024 for the study.General Information Questionnaire,Financial Toxicity Scale for Cancer Family Caregivers,and Impact of Event Scale-Revised were used to survey the study participants.Latent categories of financial toxicity were analyzed using Mplus 8.0.Ordered Logistic regression was used to analyze the influencing factors of latent categories of financial toxicity among caregivers of cancer patients with chemotherapy.Multiple linear regression was used to analyze the relationship between latent categories of financial toxicity and PTSD.ResultsA total of 256 questionnaires were distributed and 242 valid questionnaires were recovered,with an effective recovery rate of 94.53%(242/256).The financial toxicity of 242 caregivers of cancer patients undergoing chemotherapy were classified into three latent categories,including low financial toxicity-low behavior change group(9.92%),moderate financial toxicity-moderate coping potential group(36.78%),and high financial toxicity-high coping difficulty group(53.31%).Ordered Logistic regression analysis showed that work status,occupation,and educational level were influencing factors of potential categories of financial toxicity for caregivers of cancer patients undergoing chemotherapy(P<0.05).Caregivers in moderate financial toxicity-moderate coping potential group and high financial toxicity-high coping difficulty group had more severe PTSD compared with caregivers in low financial toxicity-low behavior change group

关 键 词：肿瘤 化疗 照顾者 经济毒性 创伤后应激障碍 潜在剖面分析 

分 类 号：R73[医药卫生—肿瘤]