慢性阻塞性肺疾病-支气管扩张重叠综合征发病的影响因素分析  

Analysis of Influencing Factors of Chronic Obstructive Pulmonary Disease and Bronchiectasis Overlap Syndrome

作　　者：萨其拉 SA Qila(Department of Respiratory and critical Medicine,International Mongolian Hospital of Inner Mongolia,Hohhot,Inner Mongolia 010010,China)

机构地区：[1]内蒙古自治区国际蒙医医院呼吸与危重症医学科,内蒙古呼和浩特010010

出　　处：《中国医药指南》2025年第6期109-111,共3页Guide of China Medicine

摘　　要：目的通过回顾性分析慢性阻塞性肺疾病(COPD)-支气管扩张重叠综合征患者的病例资料,对影响其发病的相关因素进行探讨。方法研究对象选取内蒙古自治区国际蒙医医院2021年2月至2023年6月收治的COPD患者180例,入院治疗时间为2021年2月至2023年6月,根据患者有无合并支气管扩张分成单纯组(未合并支气管扩张,n=100)与重叠组(合并支气管扩张,n=80)。两组基线资料进行回顾性分析,并对比两组的肺功能指标、血气指标及临床症状,通过多因素Logistic回归分析对发病影响因素进行探讨。结果全部180例COPD患者中,80例患者合并支气管扩张,COPD-支气管扩张重叠综合征的发生率为44.44%(80/180)。多因素分析显示,COPD-支气管扩张重叠综合征发病的独立危险因素包括了痰培养铜绿假单胞菌阳性、COPD评估测试(CAT)评分、肺结核史、住院时间、年龄及吸烟史(P<0.05)。结论COPD-支气管扩张重叠综合征发病的独立危险因素为痰培养铜绿假单胞菌阳性、CAT评分、肺结核史、住院时间、年龄及吸烟史,临床中应结合发病影响因素制定有针对性的干预对策,以改善患者预后,促进其病情康复。Objective To retrospectively analyze the clinical data of patients with chronic obstructive pulmonary disease(COPD)-bronchiectasis overlap syndrome and explore the related factors affecting its incidence.Methods A total of 180 patients with COPD admitted to the International Mongolian Medicine Hospital of Inner Mongolia Autonomous Region from February 2021 to June 2023 were selected.The admission time was from February 2021 to June 2023,and the patients were divided into simple group(without bronchiectasis,n=100)and overlap group(with bronchiectasis,n=80).The baseline data of the two groups were retrospectively analyzed,and the pulmonary function indexes,blood gas indexes and clinical symptoms of the two groups were compared.The influencing factors of the disease were explored by multivariate Logistic regression analysis.Results Among the 180 patients with COPD,80 patients had bronchiectasis,and the incidence of COPD-bronchiectasis overlap syndrome was 44.44%(80/180).Multivariate analysis showed that the independent risk factors of COPD bronchiectasis overlap syndrome included positive Pseudomonas aeruginosa in sputum culture,CAT,history of tuberculosis,length of hospital stay,age and smoking history(P<0.05).Conclusions The independent risk factors of COPD bronchiectasis overlap syndrome are positive Pseudomonas aeruginosa in sputum culture,CAT,history of pulmonary tuberculosis,length of hospital stay,age and smoking history.In clinical practice,targeted intervention strategies should be formulated according to the influencing factors to improve the prognosis of patients and promote their recovery.

关 键 词：慢性阻塞性肺疾病 支气管扩张 重叠综合征 影响因素 

分 类 号：R563.9[医药卫生—呼吸系统]