覆膜支架与介入联合治疗食管癌食管气管瘘的效果  

Effect of covered stent and interventional therapy for esophageal-tracheal fistula in esophageal cancer

作　　者：贾云明 朱海波[1] 耿家波 周杨杨 JIA Yunming;ZHU Haibo;GENG Jiabo;ZHOU Yangyang(Department of Interventional Therapy,Zibo Municipal Hospital,Linzi District People's Hospital of Zibo City,Zibo,Shandong 255400,China)

机构地区：[1]淄博市市立医院淄博市临淄区人民医院介入治疗科,山东淄博255400

出　　处：《医药前沿》2025年第6期41-44,共4页Journal of Frontiers of Medicine

摘　　要：目的观察食管癌食管气管瘘患者行覆膜支架与介入联合治疗的效果。方法选取2021年1月-2023年6月淄博市市立医院收治的50例食管癌食管气管瘘患者,根据治疗方法不同分为对照组与观察组各25例。对照组予以覆膜支架治疗,观察组予以覆膜支架治疗+介入治疗。比较两组的支架置入成功情况、生存情况、并发症发生情况、治疗效果。结果治疗后,观察组支架置入成功率、骨髓抑制率高于对照组,癌胚抗原、糖类抗原19-9、支架再次狭窄率低于对照组;治疗后1、3个月,观察组总有效率均高于对照组;治疗后3、6个月,观察组生存率高于对照组,差异有统计学意义(P<0.05)。结论对食管癌食管气管瘘患者行覆膜支架治疗与介入治疗效果明显,可提高支架植入成功率和生存率,降低癌胚抗原、糖类抗原19-9水平,以及支架再狭窄率。Objective To observe the effect of covered stent treatment and interventional therapy for patients with esophageal-tracheal fistula in esophageal cancer.Methods A total of 50 patients with esophageal-tracheal fistula in esophageal cancer admitted to Zibo Municipal Hospital from January 2021 to June 2023 were selected.According to different treatment methods,they were divided into a control group and an observation group,with 25 cases in each group.The control group was treated with covered stent,and the observation group was treated with covered stent+interventional therapy.The successful stent placement,survival,complication events,and treatment efficacy were compared between the two groups.Results After treatment,the successful stent placement rate and the incidence of myelosuppression in the observation group were higher than those in the control group,while the levels of carcinoembryonic antigen,carbohydrate antigen 19-9,and the rate of stent restenosis were lower than those in the control group;at 1 and 3 months after treatment,the total effective rate of the observation group was higher than that of the control group;at 3 and 6 months after treatment,the survival rate of the observation group was higher than that of the control group,and the differences were statistically significant(P<0.05).Conclusions Covered stent treatment combined with interventional therapy for patients with esophageal-tracheal fistula in esophageal cancer has obvious effects,which can improve the successful rate of stent implantation and survival rate,reduce the levels of carcinoembryonic antigen and carbohydrate antigen 19-9,and decrease the rate of stent restenosis.

关 键 词：食管癌 食管气管瘘 覆膜支架治疗 介入治疗 治疗效果 安全性 

分 类 号：R735[医药卫生—肿瘤]