益气活血化痰汤对降低冠心病稳定型心绞痛气虚血瘀证PCI术后不良事件发生率的效果  

Clinical observation of Yiqi Huoxue Huatan Decoction on adverse events after PCI in patients with stable angina pectoris of coronary heart disease with Qi deficiency and blood stasis syndrome

作　　者：袁王菲 郑涛 YUAN Wangfei;ZHENG Tao(Department of Cardiology,the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang,Guizhou 550001,China)

机构地区：[1]贵州中医药大学第一附属医院心内科,贵州贵阳550001

出　　处：《医药前沿》2025年第6期91-93,共3页Journal of Frontiers of Medicine

摘　　要：目的观察益气活血化痰汤对降低冠状动脉粥样硬化性心脏病(简称冠心病)稳定型心绞痛气虚血瘀证经皮冠状动脉介入治疗(PCI)术后再发心肌梗死、靶血管血运重建、心源性死亡等心血管不良事件发生率的效果。方法选取2022年1月-2023年1月于贵州中医药大学第一附属医院行PCI术的106例冠心病稳定型心绞痛气虚血瘀证患者,根据患者是否服用益气活血化痰汤分为对照组和活血组各53例。对照组PCI术后给予常规药物治疗,活血组在对照组常规治疗基础上给予益气活血化痰汤。比较两组治疗6个月后再发心肌梗死、靶血管血运重建、心源性死亡等心血管不良事件发生的情况。结果活血组再发心肌梗死率为3.77%,对照组再发心肌梗死率为9.43%;活血组靶血管重建率为1.89%,对照组靶血管重建率为7.54%;活血组无心源性死亡患者,对照组心源性死亡率为3.77%;活血组的心血管累积不良事件总发生率低于对照组,差异有统计学意义(P<0.05)。结论益气活血化痰汤可明显降低冠心病稳定型心绞痛气虚血瘀证患者PCI术后不良事件的发生率。Objective To observe the effect of Yiqi Huoxue Huatan Decoction on adverse events after percutaneous coronary intervention(PCI)in patients with stable angina pectoris of coronary heart disease with Qi deficiency and blood stasis syndrome,such as recurrent myocardial infarction,target vessel revascularization,cardiac death,all-cause death,and other adverse cardiovascular events.Methods A total of 106 patients with stable angina pectoris of coronary heart disease with Qi deficiency and blood stasis syndrome who underwent PCI at the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine from January 2022 to January 2023 were selected.They were divided into control group and huoxue group,with 53 patients in each group.The control group received conventional medication treatment after PCI,while the huoxue group received Yiqi Huoxue Huatan Decoction in addition to the conventional treatment group.The incidence of cardiovascular adverse events such as recurrent myocardial infarction,target vessel revascularization,and cardiac death between two groups after 6 months of treatment were compared.Results The recurrence rate of myocardial infarction in the Huoxue group was 3.77%,and the recurrence rate of myocardial infarction in the control group was 9.43%;the target vessel reconstruction rate of the huoxue group was 1.89%,and the target vessel reconstruction rate of the control group was 7.54%;there was no cardiac death in the huoxue group,and the cardiac death rate in the control group was 3.77%;the incidence of cardiovascular cumulative adverse events in the huoxue group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusions Yiqi Huoxue Huatan Decoction can significantly reduce the incidence of adverse events after PCI in patients with stable angina pectoris of coronary heart disease with Qi deficiency and blood stasis syndrome.

关 键 词：冠心病 稳定型心绞痛 经皮冠脉介入治疗 心血管不良事件 益气活血化痰汤 

分 类 号：R286[医药卫生—中药学]