“护场”理论指导下的不同剂型自拟“止痒合剂”治疗急性肛门湿疹的临床效果比较  

Clinical effect of different dosage forms of self-made"Zhiyang Mixture"on acute anal eczema under the guidance of"huchang"theory

作　　者：王军 丁俊 张艳 陈旭 WANG Jun;DING Jun;ZHANG Yan;CHEN Xu(Department of Anorectal,He County Hospital of Traditional Chinese Medicine,Ma'anshan,Anhui 238200,China;Department of Pharmacy,He County Hospital of Traditional Chinese Medicine,Ma'anshan,Anhui 238200,China)

机构地区：[1]和县中医院肛肠科,安徽马鞍山238200 [2]和县中医院药剂科,安徽马鞍山238200

出　　处：《医药前沿》2025年第6期94-97,共4页Journal of Frontiers of Medicine

摘　　要：目的比较在“护场”理论指导下的不同剂型自拟“止痒合剂”治疗急性肛门湿疹(EA)的临床效果。方法选取和县中医院2022年6月-2023年6月接受治疗的59例EA患者,采用随机数字表法分为对照组和观察组,对照组30例,观察组29例。两组使用不同剂型的自拟“止痒合剂”进行治疗,对照组给予水剂治疗,观察组给予散剂治疗。比较两组中医证候积分、临床疗效及随访6个月后的复发情况。结果治疗前,两组患者中医证候积分比较,差异无统计学意义(P>0.05);治疗后,观察组中医证候积分低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。经过随访发现,观察组6个月内总复发率低于对照组,差异有统计学意义(P<0.05)。结论在对EA患者进行治疗时,采用基于“护场”理论指导的自拟“止痒合剂”散剂治疗对病情的控制效果较好,能够有效降低患者中医证候积分,且经随访发现,半年内采用散剂外用的患者复发率较低,值得临床应用。Objective To explore the clinical effect of different dosage forms of self-made"Zhiyang Mixture"on acute anal eczema(EA)under the guidance of"huchang"theory.Methods From June 2022 to June 2023,a total of 59 patients with EA treated in He County Hospital of Traditional Chinese Medicine were selected.According to the random number table method,they were divided into control group and observation group,30 cases in control group and 29 cases in observation group.The two groups were treated with different dosage forms of self-made"Zhiyang Mixture",the control group was treated with water antipruritic mixture,and the observation group was treated with powder antipruritic mixture.The traditional Chinese medicine syndrome scores,clinical efficacy,and recurrence after 6 months of follow-up were compared between the two groups.Results Before treatment,there was no significant difference in traditional Chinese medicine syndrome scores between the two groups(P>0.05).After treatment,the traditional Chinese medicine syndrome score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).After follow-up,the total recurrence rate of the observation group within 6 months was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusions In the treatment of EA patients,the self-made"Zhiyang Mixture"based on the theory of"huchang"theory has a better control effect on the disease,which can effectively reduce the traditional Chinese medicine syndrome score of patients.After follow-up,the recurrence rate of patients with external use of powder within half a year was lower,and it was recommended to be popularized and applied by clinical medical staff.

关 键 词：护场理论 止痒合剂 急性肛门湿疹 中医证候积分 水剂 散剂 

分 类 号：R283[医药卫生—中药学]