原料药合成工艺中自然冷源冷却技术经济分析  

The Economic Analysis on the Natural Cold Source Cooling Technology of Synthesis Process of the Active Pharmaceutical Ingredients

作　　者：薛永明 冯江发 姜宇 薛红香 张峰 Xue Yongming;Feng Jiangfa;Jiang Yu;Xue Hongxiang;Zhang Feng(Shandong Pharmaceutical Industry Design Institute Co.,Ltd,Jinan,250101;Tai'an Special Equipment Inspection Institute,Tai'an,271000;CNOOC Petrochemical Engineering Co.,Ltd,Jinan,250101)

机构地区：[1]山东省医药工业设计院有限公司,济南250101 [2]泰安市特种设备检验研究院,泰安271000 [3]中海油石化工程有限公司,济南250101

出　　处：《制冷与空调(四川)》2025年第1期89-93,132,共6页Refrigeration and Air Conditioning

摘　　要：针对原料药合成工艺对常温乙二醇溶液的冷却需求,提出一种自然冷源与机械制冷相结合的复合制冷系统。研究结果表明,在冬季和过渡季节使用时,能够显著降低制冷能耗和运行电耗,提高产品运行的经济效益,符合国家的节能降碳政策。A compound refrigeration system combining natural cold sources and mechanical refrigeration is proposed,which is employed to meet the cooling requirements of ethylene glycol solution with normal temperature in the synthetic process of active pharmaceutical ingredients The research results show that both the cooling energy consumption and operating power consumption can be significantly reduced during winter and transition seasons,and therefore improve the economic benefits of the synthetic products of active pharmaceutical ingredients,which means the cooling technology comply with the national energy conservation and carbon reduction policies.

关 键 词：原料药合成 自然冷源 冷却技术 乙二醇溶液 机械制冷 

分 类 号：TU83[建筑科学—供热、供燃气、通风及空调工程]