Genome of tropical bed bug Cimex hemipterus(Cimicidae,Hemiptera)reveals tetraspanin expanded in bed bug ancestor  

作　　者：Sean Tsz Sum Law Wenyan Nong Chade Li Tze Kiu Chong Ho Yin Yip Thomas Swale Siu Wai Chiu Roger Yat-Nork Chung Hon-Ming Lam Samuel Y.S.Wong Hung Wong Jerome H.L.Hui 

机构地区：[1]School of Life Sciences,Simon F.S.Li Marine Science Laboratory,State Key Laboratory of Agrobiotechnology,Institute of Environment,Energy and Sustainability,The Chinese University of Hong Kong,Hong Kong,China [2]Dovetail Genomics,The United States of America [3]School of Life Sciences,The Chinese University of Hong Kong,Hong Kong,China [4]School of Public Health and Primary Care,CUHK Institute of Health Equity,The Chinese University of Hong Kong,Hong Kong,China [5]School of Life Sciences,State Key Laboratory of Agrobiotechnology,Institute of Environment,Energy and Sustainability,The Chinese University of Hong Kong,Hong Kong,China [6]Department of Social Work,CUHK Institute of Health Equity,Institute of Environment,Energy and Sustainability,The Chinese University of Hong Kong,Hong Kong,China

出　　处：《Insect Science》2025年第1期42-54,共13页昆虫科学(英文版)

基　　金：chromosome assembly was submitted to NCBI Assembly under accession number JASJUQ000000000 in NCBI;generated in this study have been deposited into the NCBI database under the BioProject accession PRJNA713496;the genome annotation files were deposited in the Figshare(https://figshare.com/s/d9956fa56189ac8938c0).

摘　　要：Cimex species are ectoparasites that exclusively feed on warm-blooded animals such as birds and mammals.Three cimicid species are known to be persistent pests for humans,including the tropical bed bug Cimex hemipterus,common bed bug Cimex lectularius,and Eastern bat bug Leptocimex boueti.To date,genomic information is restricted to the common bed bug C.lectularius,which limits understanding their biology and to provide controls of bed bug infestations.Here,a chromosomal-level genome assembly of C.hemipterus(495 Mb[megabase pairs])contained on 16 pseudochromosomes(scaffold N50=34 Mb),together with 9 messenger RNA and small RNA transcriptomes were obtained.In comparison between hemipteran genomes,we found that the tetraspanin superfamily was expanded in the Cimex ancestor.This study provides the first genome assembly for the tropical bed bug C.hemipterus,and offers an unprecedented opportunity to address questions relating to bed bug infestations,as well as genomic evolution to hemipterans more widely.

关 键 词：bedbug GENOME microRNA SESQUITERPENOID TETRASPANIN 

分 类 号：Q96[生物学—昆虫学]