基于芳酰胺酰腙大环的超分子聚合物的构建  

The construction of supramolecular polymers based on aromatic acylhydrazone macrocycle

作　　者：周明利 邓何 赵佳豪 李倩 杨春江[1] 王璐 Mingli Zhou;He Deng;Jiahao Zhao;Qian Li;Chunjiang Yang;Lu Wang(Department of Ultrasound,Children's Hospital of Chongqing Medical University,National Clinical Research Center for Child Health and Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,Chongqing Engineering Research Center of Stem Cell Therapy,Chongqing 400014,China;The Institute for Advanced Studies,Wuhan University,Wuhan 430072,China;The Affiliated Yongchuan Hospital of Chongqing Medical University,Chongqing 402160,China;Chongqing Key Laboratory of Ultrasound Molecular Imaging and Therapy,Institute of Ultrasound Imaging,Chongqing 400010,China)

机构地区：[1]重庆医科大学附属儿童医院超声科,国家儿童健康与疾病临床医学研究中心,儿童发育疾病研究教育部重点实验室,重庆市干细胞治疗工程技术研究中心,重庆400014 [2]武汉大学高等研究院,武汉430072 [3]重庆医科大学附属永川医院,重庆402160 [4]超声分子影像诊疗重庆市重点实验室,超声影像学研究所,重庆400010

出　　处：《中国科学:化学》2025年第2期514-520,共7页SCIENTIA SINICA Chimica

基　　金：国家自然科学基金(编号:21801194)资助项目。

摘　　要：通过多种非共价作用的多层次组装,可以构建出结构更加复杂、层次更有序且性能独特的新型超分子聚合物.本文介绍了一种新颖的超分子聚合物SP-1,以及通过主客体作用进一步形成的交联超分子聚合物网络SP-2.利用金属配位和主客体结合两种非共价相互作用,实现了酰腙大环MC与银离子的配位组装,并与双吡啶盐BP进行二次组装.酰腙大环MC具有良好的平面性,有利于与金属离子配位,形成SP-1后,其形貌由囊泡转变为纳米颗粒.SP-1进一步与BP交联后,纳米颗粒转变为规则的小尺寸纳米棒结构,形成SP-2.研究表明,酰腙大环MC在超分子聚合物构建中具有巨大潜力,并揭示了主客体相互作用在构建复杂超分子结构中的重要性.To construct novel supramolecular polymers with more complex structures,ordered hierarchies,and unique properties,a multilevel assembly using various non-covalent interactions is essential.This study presents a novel supramolecular polymer,SP-1,and its further crosslinked supramolecular polymer network,SP-2,formed via host-guest interactions.Through the combined use of metal coordination and host-guest interactions,we achieved the coordination assembly of hydrazone macrocycle MC with silver ions,followed by secondary assembly with bipyridinium salt BP.The planar structure of MC facilitates coordination with metal ions.Upon forming SP-1,its morphology transitions from vesicles to nanoparticles.Subsequent crosslinking of SP-1 with BP transforms these nanoparticles into welldefined,small-sized nanorods,resulting in SP-2.The study highlights the significant potential of MC in supramolecular polymer construction and underscores the critical role of host-guest interactions in building complex supramolecular structures.

关 键 词：超分子聚合物 大环 金属配位作用 主客体作用 多层次组装 

分 类 号：TB3[一般工业技术—材料科学与工程]