健康体检人群心理健康状况与代谢综合征的相关性  

Correlation between mental health status and metabolic syndrome in health checkup population

作　　者：何宏海 张小莲 郝小燕 车颖 赵威[1] 王宏利[1] 田磊[1] 吴华[1] 王鹏[1] He Honghai;Zhang Xiaolian;Hao Xiaoyan;Che Ying;Zhao Wei;Wang Hongli;Tian Lei;Wu Hua;Wang Peng(Medical Examination Center of Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院健康管理(体检)中心,北京100191

出　　处：《中华健康管理学杂志》2025年第2期127-133,共7页Chinese Journal of Health Management

基　　金：北京大学第三医院院队列建设项目(BYSYDL2021003)。

摘　　要：目的分析健康体检人群心理健康状况与代谢综合征(MetS)的相关性。方法本研究为横断面研究,采取整群抽样的方法,回顾性选取2019年1月至2023年12月在北京大学第三医院体检中心进行健康体检的受检者2920例,收集其一般资料、体格检查、生化指标、人体成分及症状自评量表(SCL-90)测评结果。根据纳入排除标准,共纳入2813例研究对象,按是否患有MetS分为MetS组和非MetS组,比较组间一般人口学资料、人体成分、血生化和SCL-90测评结果的差异。使用二元logistic回归分析心理健康状况与MetS的相关性。结果纳入的2813例受检者中,男1576例(56.0%),女1237例(44.0%),年龄(41.7±11.0)岁;MetS组586例(20.8%),非MetS组2227例(79.2%)。MetS组年龄、体重指数、腰围、收缩压、舒张压、总胆固醇、甘油三酯、低密度脂蛋白胆固醇(LDL-C)、空腹血糖、糖化血红蛋白(HbA 1c)、游离甲状腺素(FT4)、总三碘甲状腺原氨酸(TT3)、游离三碘甲状腺原氨酸(FT3)、腰臀比、内脏脂肪面积、体脂百分比、尿酸/肌酐、同型半胱氨酸(Hcy)、天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)水平以及躯体化、敌对、偏执和其他因子评分均高于非MetS组(均P<0.05),而高密度脂蛋白胆固醇(HDL-C)和估算的肾小球滤过率(eGFR)水平均低于非MetS组(均P<0.05)。MetS组男性、SCL-90测评总体、躯体化、人际关系敏感、敌对、偏执和其他因子的阳性占比均高于非MetS组(均P<0.05)。多因素分析结果显示,SCL-90测评阳性者较阴性者MetS的患病风险增加1.34倍(OR=1.34,95%CI:1.06~1.68,P=0.014)。其中躯体化(OR=2.02,95%CI:1.25~3.28,P=0.004)和敌对(OR=1.61,95%CI:1.02~2.56,P=0.042)因子阳性者MetS的患病风险增高。结论不良的心理健康状况可增加MetS的患病风险。ObjectiveTo analyze the correlation between mental health status and metabolic syndrome(MetS)in health checkup people.MethodsIt was a cross-sectional study,2920 participants who received health checkup in the Health Examination Center of Peking University Third Hospital from January 2019 to December 2023 were selected using cluster sampling method.Their general information,physical examination,biochemical indicators,body composition,and self-evaluation scores on the Symptom Checklist-90(SCL-90)were collected.According to the inclusion and exclusion criteria,a total of 2813 study subjects were included,and divided into the MetS group and the non-MetS group based on whether they had MetS.The differences in general demographic information,body composition,blood biochemistry,and SCL-90 scores between the two groups were compared.Binary Logistic regression analysis was used to explore the correlation between mental health status and MetS.ResultsOf the 2813 subjects included,1576 were males(56.0%)and 1237 were females(44.0%),with an average age of(41.7±11.0)years,the MetS group had 586 cases(20.8%)and the non-MetS group had 2227 cases(79.2%).The MetS group had higher levels of age,body mass index,waist circumference,systolic blood pressure,diastolic blood pressure,total cholesterol,triglycerides,low density lipoprotein cholesterol(LDL-C),fasting blood glucose,glycosylated hemoglobin(HbA 1c),free thyroxine(FT4),total triiodothyronine(TT3),free triiodothyronine(FT3),waist-to-hip ratio,visceral fat area,body fat percentage,uric acid/creatinine,homocysteine(Hcy),aspartate aminotransferases(AST),and alanine transaminase(ALT)levels,as well as higher scores for somatization,hostility,paranoia,and other factor compared to the non-MetS group(all P<0.05),while high density lipoprotein cholesterol(HDL-C)and estimated glomerular filtration rate(eGFR)levels were lower than those in the non-MetS group(all P<0.05).The proportion of male,and the positive rates of SCL-90,somatization,interpersonal sensitivity,hostility,paranoia and ot

关 键 词：代谢综合征X 精神卫生 心理测定学 健康体检 相关性分析 横断面研究 

分 类 号：R58[医药卫生—内分泌]