On P-value Combination Procedures  

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作  者:Zhen Meng Yuke Shi Jinyi Lin Qizhai Li 

机构地区:[1]School of Statistics,Capital University of Economics and Business,Beijing 100070,P.R.China [2]Academy of Mathematics and Systems Science,Chinese Academy of Sciences,Beijing 100190,P.R.China [3]University of Chinese Academy of Sciences,Beijing 100049,P.R.China

出  处:《Acta Mathematica Sinica,English Series》2025年第2期569-587,共19页数学学报(英文版)

基  金:Supported by the CAS Project for Young Scientists in Basic Research(Grant No.YSBR-034);National Nature Science Foundation of China(Grant Nos.12325110,12201432)。

摘  要:Combining p-values is a well-known issue in statistical inference. When faced with a study involving m p-values, determining how to effectively combine them to arrive at a comprehensive and reliable conclusion becomes a significant concern in various fields, including genetics, genomics, and economics, among others. The literature offers a range of combination strategies tailored to different research objectives and data characteristics. In this work, we aim to provide users with a systematic exploration of the p-value combination problem. We present theoretical results for combining p-values using a logarithmic transformation, which highlights the benefits of this approach. Additionally, we propose a combination strategy together with its statistical properties utilizing the gold section method, showcasing its performance through extensive computer simulations. To further illustrate its effectiveness, we apply this approach to a real-world scenario.

关 键 词:Logarithm transformation power p-value combination RANK 

分 类 号:O212.1[理学—概率论与数理统计]

 

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