中药红芪多糖的提取分离、结构修饰及其药理活性  

Extraction and separation,structural modification and pharmacological activity of polysaccharides from Chinese medicine Radix Hedysari

作　　者：原梦瑶 康淑荷 陆丽娜[1,2,3,4] 李佳 罗兴平[1,2,3,4] YUAN Mengyao;KANG Shuhe;LU Lina;LI Jia;LUO Xingping(Key Laboratory of Environment-Friendly Composites of the State Ethnic Affairs Commission,Lanzhou 730106,Gansu Province,China;Gansu Provincial Biomass Function Composites Engineering Research Center,Lanzhou 730106,Gansu Province,China;Key Laboratory for Utility of Environment-Friendly Composite Materials and Biomass in University of Gansu Province,Lanzhou 730106,Gansu Province,China;School of Chemical Engineering,Northwest Minzu University,Lanzhou 730106,Gansu Province,China)

机构地区：[1]环境友好复合材料国家民委重点实验室,甘肃兰州730106 [2]甘肃省生物质功能复合材料工程研究中心,甘肃兰州730106 [3]甘肃省高校环境友好复合材料及生物质利用省级重点实验室,甘肃兰州730106 [4]西北民族大学化工学院,甘肃兰州730106

出　　处：《化学工程》2025年第2期57-63,77,共8页Chemical Engineering(China)

基　　金：中央高校基本科研业务费(31920210037,31920220160,31920230144);国家自然科学基金资助项目(21865028)。

摘　　要：红芪(Radix Hedysari)为名贵中药材,具有补气利血、固表止汗、敛疮排毒等功效。其主要活性成分之一红芪多糖,具有调节免疫系统、抗肿瘤、延缓衰老、降低血糖以及缓解肝损伤等药理活性。文中综述了红芪多糖的提取、分离、结构、结构修饰及其药理活性的最新研究进展,以期为中药红芪植物资源和红芪多糖的进一步研究和产业化提供科学依据。Radix Hedysari is a precious Chinese medicinal material that has the effects of tonifying qi and promoting blood circulation,consolidating the surface and stopping sweating,controlling sores and detoxification.One of its main active ingredients,Radix Hedysari polysaccharide,has pharmacological activities such as immune system regulation,anti-tumor,delaying senescence,lowering blood sugar,and alleviating liver damage.This article reviewed the latest research progress on the extraction,separation,structure,structural modification,and pharmacological activity of Radix Hedysari polysaccharide,in order to provide scientific basis for further research and industrialization of traditional Chinese medicine Radix Hedysari plant resources and Radix Hedysari polysaccharide.

关 键 词：红芪多糖 分离纯化 结构鉴定 结构修饰 药理活性 

分 类 号：R284.2[医药卫生—中药学]