乳腺良恶性肿瘤患者超微血管显像血管特征与生物学行为关联性分析  

Relationship between blood vessel characteristics and biological behavior in patients with benign and malignant breast tumors by ultramicrovascular imaging

作　　者：王勤 Wang Qin(Department of Ultrasound,Henan Hongli Hospital,Xinxiang 453400,China)

机构地区：[1]河南宏力医院超声科,新乡453400

出　　处：《实用医学影像杂志》2025年第1期49-53,共5页Journal of Practical Medical Imaging

摘　　要：目的 探讨乳腺良恶性肿瘤患者超微血管显像血管特征与生物学行为的相关性,以期为临床早期评估肿瘤进展程度、制定治疗方案提供参考。方法 选取我院2020年6月至2023年3月就诊的乳腺肿瘤患者128例作为研究对象,入院后均行超微血管显像检查,比较乳腺良恶性肿瘤微血管形态分型,对超微血管显像图像采用Adler半定量法进行血流分级,比较不同生物学行为乳腺癌Adler分级,分析乳腺癌生物学行为与Adler分级的关系。结果 与乳腺良性肿瘤比较,乳腺恶性肿瘤超微血管显像微血管形态分型中残根型、蟹足型较多,无血管型、线型、树枝型较少(P<0.05);Adler分级<Ⅱ级、Adler分级≥Ⅱ级乳腺癌患者在肿瘤直径、淋巴结转移、分化程度、雌激素受体(ER)、孕激素受体(PR)、人表皮生长因子受体2(HER-2)、Ki-67表达方面比较差异有统计学意义(P<0.05);经Logistic回归方程分析发现,淋巴结转移、ER阳性、PR阳性、HER2阳性、Ki-67高表达均为乳腺癌Adler分级的相关影响因素。结论 超微血管显像可用于乳腺良恶性肿瘤鉴别中,且超微血管显像血管特征与乳腺癌生物学行为密切相关,为临床针对性制定治疗方案提供参考。Objective To investigate the correlation between blood vessel characteristics and biological behavior in patients with benign and malignant breast tumors,in order to provide a reference for early clinical evaluation of tumor progression and formulation of treatment plan.Methods A total of 128 patients with breast tumors treated in our hospital from June 2020 to March 2023 were selected as the study objects.After admission,all of them were examined by ultramicrovascular imaging.The microvascular morphological classification of benign and malignant breast tumors was compared,and blood flow classification was performed by Adler semi-quantitative method.The relationship between biological behavior and Adler grading of breast cancer was analyzed.Results Compared with benign breast tumors,there were more stump type and crab foot types,but fewer vasculature types,line type,and branch type(P<0.05).There were significant differences in tumor diameter,lymph node metastasis,differentiation degree,ER,PR,HER2,and Ki-67 expression between Adler grade<Ⅱand Adler grade≥Ⅱbreast cancer patients(P<0.05).Logistic regression equation analysis showed that lymph node metastasis,ER positive,PR positive,HER2 positive,Ki-67 high expression was related to the Adler grade of breast cancer.Conclusion Ultramicrovascular imaging can be used in the differentiation of benign and malignant breast tumors,and the vascular characteristics of ultramicrovascular imaging are closely related to the biological behavior of breast cancer.

关 键 词：乳腺肿瘤 超微血管显像 生物学行为 Adler分级 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]