下肢深静脉血栓的介入机械性取栓研究进展  

Advances in interventional mechanical thrombus extraction in lower extremity deep vein thrombosis

作　　者：朱迪 马坤 周涛 苗青海 邵泽锋 ZHU Di;MA Kun;ZHOU Tao;MIAO Qinghai;SHAO Zefeng(Department of Interventional Radiology,Affiliated Hospital of Nanjing University of Chinese Medicine,Jiangsu Province Hospital of Chinese Medicine,Nanjing,Jiangsu 210029,China;不详)

机构地区：[1]南京中医药大学附属医院江苏省中医院介入科,江苏南京210029 [2]南通大学杏林学院附属南京江北医院介入医学科,江苏南京210048

出　　处：《中国临床研究》2025年第2期173-177,共5页Chinese Journal of Clinical Research

基　　金：江苏省卫生健康委员会科研项目(BJ14012);江苏省中医院人才引进项目(kgr0259);皖南医学院科研项目(JXYY202133)。

摘　　要：深静脉血栓形成(DVT)是指血液在深静脉内异常凝结,常见于下肢。DVT的形成机制主要涉及静脉血流减缓、血液高凝状态和血管内皮损伤。常见风险因素包括长时间卧床、手术后恢复、恶性肿瘤、妊娠期、遗传性血栓倾向及某些药物的使用。DVT的最严重并发症是肺动脉栓塞(PE)。此外,DVT可导致慢性并发症如血栓后综合征。对于特定高危患者,可考虑溶栓治疗或置入下腔静脉滤器以预防PE。随着医疗技术的不断进步,机械性血栓清除装置作为一种新型治疗手段,逐渐在临床中得到广泛应用,为清除静脉血栓提供了一种微创且有效的方法。本文将通过各种装置原理、治疗优势、临床应用效果综述深静脉机械性取栓技术应用在临床的最新进展。Deep vein thrombosis(DVT)refers to the abnormal clotting of blood within deep veins,predominantly in the lower extremities.Its formation is primarily attributed to three key factors:venous stasis,a hypercoagulable state,and endothelial injury.Common risk factors include prolonged immobilization,post-surgical recovery,malignant tumor,pregnancy,hereditary thrombophilia and certain medications.The most significant complication of DVT is pulmonary embolism(PE),while chronic complications such as post-thrombotic syndrome(PTS)can also occur.In high-risk patients,thrombolytic therapy or inferior vena cava filters may be used to prevent PE.Advances in medical technology have led to the widespread use of percutaneous mechanical thrombectomy(PMT)devices,which provide a minimally invasive and effective method for removing venous thrombi.This article reviews recent developments in the clinical application of deep vein mechanical thrombus removal technologies,with a focus on the principles,therapeutic benefits,and clinical outcomes of various devices.

关 键 词：深静脉血栓 血栓后综合征 机械性血栓清除装置 大腔导管抽吸血栓 

分 类 号：R543.6[医药卫生—心血管疾病]