天津市呼吸道合胞病毒单克隆抗体在预防接种门诊的推动和实施  

Promotion and implementation of respiratory syncytial virus monoclonal antibody in vaccination clinics in Tianjin City

作　　者：丁亚兴[1] 王森 高志刚[1] 陈伟[1] 骆晓艳[1] 张国平 张颖[1] Ding Yaxing;Wang Sen;Gao Zhigang;Chen Wei;Luo Xiaoyan;Zhang Guoping;Zhang Ying(Department of Expanded Programme on Immunization,Tianjin Center for Disease Control and Prevention,Tianjin 300011,China;Department of Health and Expanded Programme on Immunization,Tianjin Bureau of Disease Prevention and Control,Tianjin 300070,China)

机构地区：[1]天津市疾病预防控制中心免疫规划所,天津300011 [2]天津市疾病预防控制局卫生与免疫规划处,天津300070

出　　处：《中华预防医学杂志》2025年第2期260-262,共3页Chinese Journal of Preventive Medicine

基　　金：天津市医学重点学科(TJYXZDXK-050A);国家疾病预防控制局公共卫生人才培养支持项目。

摘　　要：呼吸道合胞病毒(RSV)引发的婴幼儿急性下呼吸道感染是一个重要的全球公共卫生问题,疾病负担严重。在我国冬春季易并发多种呼吸道病毒叠加流行现象,从而引发儿科的就诊和住院压力。目前全球尚无获批用于儿童的RSV疫苗,而长效单克隆抗体的研发和应用给婴幼儿人群的RSV预防提供了一种新的可能性。2024年6月天津市发布《天津市呼吸道合胞病毒(RSV)单克隆抗体接种指导意见(2024年版)》,现将天津市推动RSV单克隆抗体在预防接种门诊的使用进行梳理介绍,以期为全国性RSV免疫预防策略的制定与实施提供参考信息。Acute lower respiratory infections in infants and young children,caused by respiratory syncytial virus(RSV),represent a significant global public health challenge,characterized by a substantial disease burden.During the winter and spring seasons,various respiratory viruses tend to co-circulate,leading to increased pressure on pediatric healthcare services due to heightened rates of visits and hospitalizations.Currently,there is no approved RSV vaccine available for children worldwide;however,the development and application of long-acting monoclonal antibodies present a promising avenue for the prevention of RSV in this vulnerable population.In June 2024,Tianjin released"Guidelines for the monoclonal antibody of respiratory syncytial virus in Tianjin(2024 version)",which outlines the promotion of monoclonal antibody administration in vaccination clinics throughout the region.The objective of this paper is to provide reference information that may assist in the formulation and implementation of a national RSV immunization strategy.

关 键 词：呼吸道合胞病毒 单克隆抗体 预防接种门诊 

分 类 号：R72[医药卫生—儿科]