曼氏裂头蚴病诊断技术研究进展  

Research progress on diagnostic techniques for sparganosis mansoni

作　　者：郭嘉天 林琳 卢艳 GUO Jiatian;LIN Lin;LU Yan(National Institute of Parasitic Diseases,Chinese Center for Disease Control and Prevention,Chinese Center for Tropical Diseases Research,National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,Key Laboratory on Parasite and Vector Biology,Ministry of Health,WHO Collaborating Centre for Tropical Diseases,National Center for International Research on Tropical Diseases,Ministry of Science and Technology,Shanghai 200025,China)

机构地区：[1]中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心),传染病溯源预警与智能决策全国重点实验室,国家卫生健康委员会寄生虫病原与媒介生物学重点实验室,世界卫生组织热带病合作中心,科技部国家级热带病国际研究中心

出　　处：《中国寄生虫学与寄生虫病杂志》2024年第6期776-782,789,共8页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：上海市加强公共卫生体系建设三年行动计划(2023—2025年)重点学科项目(GWVI-11.1-12);国家寄生虫资源库(NPRC-2019-194-30)。

摘　　要：曼氏裂头蚴病是由曼氏迭宫绦虫的幼虫——裂头蚴侵入人体引起的一种人兽共患寄生虫病,呈世界性分布,严重威胁人类健康。曼氏裂头蚴可在人体内移行,其寄生部位多变,所致临床症状各不相同,并且缺乏特异性表现,误诊、漏诊较为普遍,故对裂头蚴病的精确诊断尤为重要。目前已有多种方法应用于人体曼氏裂头蚴病的诊断,本文分别从病原学、影像学、免疫学和分子生物学等方面综述了曼氏裂头蚴病的常用诊断方法,以期为曼氏裂头蚴病诊断技术的进一步研究提供参考。Sparganosis mansoni is a zoonotic parasitic disease caused by infection with plerocercoid,the larval stage of Sparganum mansoni,which is prevalent globally and poses a great threat to human health.S.mansoni plerocercoid may migrate in the human body,and misdiagnosis and missed diagnosis of sparganosis mansoni are common because of variable sites of parasitization,diverse clinical symptoms and lack of specific manifestations.Precision diagnosis of sparganosis is therefore of great importance.Currently,a variety of assays have been used for the diagnosis of human sparganosis mansoni.This review summarizes the advances in the pathogenic,imaging,immunological and molecular biological techniques for diagnosis of sparganosis mansoni,so as to provide insights into further studies on the diagnostic techniques of sparganosis mansoni.

关 键 词：曼氏裂头蚴病 诊断 研究进展 

分 类 号：R532.31[医药卫生—内科学]