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作 者:王灿 樊昊 张卫 于冠宇 Can Wang;Hao Fan;Wei Zhang;Guanyu Yu(Department of Colorectal Surgery,Changhai Hospital,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,China;Department of Gastrointestinal Surgery,the First Affiliated Hospital of Bengbu Medical University,Bengbu 233004,China)
机构地区:[1]海军军医大学第一附属医院(上海长海医院)肛肠外科,上海200433 [2]蚌埠医科大学第一附属医院胃肠外科,233004
出 处:《中华结直肠疾病电子杂志》2024年第6期519-523,共5页Chinese Journal of Colorectal Diseases(Electronic Edition)
基 金:国家自然科学基金(No.82072750,No.82203137,No.82473479);海军军医大学第一附属医院基础医学研究专项(No.2023QD003,No.2023PY04);上海市卫生健康委员会卫生行业临床研究专项(No.20224Y0348)。
摘 要:我国直肠癌发病率较高,低位前切除综合征(LARS)较为常见,通过LARS评分,可以快速筛查LARS患者的严重程度,为治疗提供指导。虽然LARS评分快捷有效且具有较高的敏感度,但随着LARS诊断标准的更新及对LARS研究的深入,LARS评分的特异度饱受争议,其内容也有待更新。LARS严重影响直肠癌术后患者的生活质量,目前缺乏准确评估和精准预测术后LARS的工具。该文旨在综述LARS评分的研制与应用,总结目前存在的争议,为研制新的评分工具提供帮助。The incidence of rectal cancer is relatively high in China,and low anterior resection syndrome(LARS)is common.The LARS score can be utilized for rapid screening of LARS patients’severity and provide treatment guidance.Despite its speed,effectiveness,and high sensitivity,the specificity of the LARS score has been a subject of controversy due to evolving diagnostic criteria and deepening research on LARS.Therefore,its content requires updating.LARS significantly impacts the postoperative quality of life for patients with rectal cancer,and there is currently a lack of accurate assessment and precise prediction tools for postoperative LARS.This article aims to review the development and application of the LARS score while summarizing existing controversies to aid in the development of new scoring tools.
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