补骨脂性味功效及用药禁忌考证  

Textual Research on Properties,Tastes and Channel Tropism of Buguzhi(Psoraleae Fructus)

作　　者：鄢羽欣 王红丽 黄锦贤 刘雪梅[1] 楚淑芳[1] YAN Yuxin;WANG Hongli;HUANG Jinxian;LIU Xuemei;CHU Shufang(Shenzhen Hospital of Traditional Chinese Medicine,Shenzhen 518033,Guangdong,China;Guangzhou University of Chinese Medicine,Guangzhou 510006,Guangdong,China)

机构地区：[1]深圳市中医院,广东深圳518033 [2]广州中医药大学,广东广州510006

出　　处：《辽宁中医药大学学报》2025年第3期99-104,共6页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金(82104759);深圳市中医临床重点专科项目(深卫健中医〔2019〕22号-2)。

摘　　要：通过收集补骨脂(Psoralea corylifolia L.)在古代本草、医籍中的相关记载,系统考证了补骨脂的性味、功效、归经及用药禁忌,并结合现代研究成果,探讨其在中医药领域的潜在价值。经考证,发现补骨脂有“婆固脂”“破故纸”“胡韭子”等别称,从唐宋至明清时期其功效主治、性味归经逐渐演变及扩展,对比2020版《中华人民共和国药典》,其主治增添了治疗外伤腰痛、牙痛、耳鸣不明、风寒湿痹证等;删除了其味甘,性大温,入心包经、肝经、大肠经等内容,而现代研究表明补骨脂具有保护心血管、抗肝癌、抗结肠癌等作用,这一发现为其在中医学与现代医学之间的桥梁作用提供了强有力的证据,因此建议对性味及归经进行补充。在古代药学文献中,关于补骨脂的使用禁忌包括了多个方面,如配伍禁忌、证候禁忌、妊娠禁忌和药后饮食禁忌等,然而目前《中华人民共和国药典》中并无禁忌记载,故对补骨脂的禁忌认识仍有待深入。该文旨在拓宽中药材补骨脂的研究视野,同时为其在新药开发领域的深入探索及临床实践的广泛应用奠定坚实的理论基础,以期促进补骨脂价值的全面挖掘与利用。By collecting relevant records in ancient herbs and medical texts,we systematically verified properties and tastes,efficacy,channel tropism and contraceptive use of Buguzhi(Psoraleae Fructus),and combined modern research findings to explore its potential value in the field of Chinese medicine.After examination,it was found that Buguzhi(Psoraleae Fructus)contained“Poguzhi”“Hujiuzi”and other aliases have gradually evolved and expanded from the Tang and Song Periods to the Ming and Qing Dynasties,and compared to the 2020 edition of the Pharmacopoeia of the People's Republic of China,its main treatment includes the treatment of injury and low back pain,toothache,ear and sight ambiguity,wind chill and paralysis,etc.Pharmacopoeia of the People's Republic of China removed the contents of its flavor,sexual warmth,inner cardiac meridian,liver meridian,and large intestine meridian,but modern research has shown that Buguzhi(Psoraleae Fructus)has cardiovascular protection,anti-cancer,anti-cancer of colon and so on.This finding provides a strong proof for its bridging role between traditional and modern medicine.Therefore,it is suggested that the properties and tastes and channel tropism should be supplemented.The incompatibility of Buguzhi(Psoraleae Fructus)in ancient Chinese herbal medicine includes incompatibility of drugs in prescription,incompatibility of drugs in pattern,incompatibility of pregnant women and incompatibility of drugs in diet.This paper aims to broaden the research field of Buguzhi(Psoraleae Fructus)in Chinese herbal medicine,and at the same time lay a solid theoretical foundation for its in-depth exploration in the field of new drug development and wide application in clinical practice,with a view to promoting the full exploitation and utilization of Buguzhi(Psoraleae Fructus)value.

关 键 词：补骨脂 别名 功效主治 性味归经 禁忌 

分 类 号：R282.74[医药卫生—中药学]