电针治疗非急性期周围性面瘫的Meta分析  

作　　者：方菲 边致远 王镓炜 梁宜[2] 方剑乔[2] 孙晶[2] 

机构地区：[1]浙江中医药大学,310053 [2]浙江中医药大学附属第三医院,310009

出　　处：《浙江临床医学》2025年第2期234-237,共4页Zhejiang Clinical Medical Journal

摘　　要：目的评价电针治疗非急性期周围性面瘫的临床疗效,为临床实践提供科学的循证医学证据。方法检索至2023年7月7日中国知网、万方数据库、维普中文生物医学期刊数据库、中国生物医学文献数据库、PubMed、Cochrane图书馆、Web of Science7个公开数据库中关于电针治疗非急性期周围性面瘫的临床随机对照试验。运用Note Express软件筛选符合标准文献,运用Cochrane系统对纳入文献进行资料提取及质量评价,将以H-B为评判指标的总有效率、治愈率,sunnybrook评分,Portmann评分及面瘫评分等为结局指标,采用Review Manage5.3软件进行异质性检验及Meta分析。结果共检索出文献745篇,最终纳入8篇,共计患者452例。Meta分析显示:电针组对于非急性期周围性面瘫的总有效率(RR=1.23,95%CI:1.12~1.34,P<0.00001)和治愈率(RR=2.14,95%CI:1.61~2.85,P<0.00001),在改善非急性期周围性面瘫患者sunnybrook静态下评分(SMD=0.73,95%CI:0.39~1.08,P<0.0001)、随意肌运动下评分(SMD=0.55,95%CI:0.20~0.89,P=0.002),Portmann评分及面瘫评分(SMD=2.58,95%CI:1.62~3.53,P<0.00001)等方面均优于对照组疗法。结论电针治疗非急性期周面瘫的疗效较其他疗法有一定优越性。但由于本研究纳入文献的样本量有限、对照组疗法种类较少、方法学质量不高,可能产生偏倚,故需要更多高质量临床随机对照试验来验证电针治疗非急性期周围性面瘫面瘫的临床疗效。Objective To discuss the clinical effect of electroacupuncture for non-acute peripheral facial paralysis and provide scientific evidencebased medical evidence for clinical practice.Methods The clinical randomized controlled trials(RCTs)of electroacupuncture in the treatment of non-acute peripheral facial paralysis were searched in the database of China National Knowledge Infrastructure(CNKI),Wanfang,VIP Database for Chinese Technical Periodicals,Chinese Biomedical Literature Database,,PubMed,Cochrane Library Databases and Web of Science before July 7th,2023.Note Express was used to select the appropriate RCTs and the Cochrane system was used to extract the data and evaluate the quality(risk of bias)of included RCTs.The overall effective rate and cure rate based on the score of H-B,the sunnybrook score,the Protmann score and facial paralysis score were used as the outcome indicators.The Review Manage5.3 software was used to heterogeneity teat and Meta-analysis.Results A total of 745 articles were retrieved and eligible 8 RCTs were included,involving 452 patients.The results of Meta-analysis shows that:compared with the control group,the electroacupuncture in the treatment of nonacute peripheral facial paralysis has significant advantages in raising the overall outcome effective rate(RR=1.23,95%CI:1.12~1.34,P<0.00001),and the cure rate(RR=2.14,95%CI:1.61~2.85,P<0.00001),also in optimizing sunnybrook score in static(SMD=0.73,95%CI:0.39~1.08,P<0.0001)and voluntary muscle movements(SMD=0.55,95%CI:0.20~0.89,P=0.002),Portmann score and the facial paralysis score(SMD=2.58,95%CI:1.62~3.53,P<0.00001).Conclusion Electroacupuncture treatment for non-acute peripheral facial paralysis has certain superiority over other treatments.However,these RCTs were low methodological quality and had limited sample size,so more high quality RCTs are needed to further verification.

关 键 词：电针 周围性面瘫 非急性期 系统评价 META分析 

分 类 号：R246.6[医药卫生—针灸推拿学]