米非司酮与乳酸依沙吖啶联合子宫颈扩张球囊引产对妊娠中期瘢痕子宫孕妇引产效果的影响  

Effect of Mifepristone and Ethacridine Lactate Combined with Cervical Dilation Balloon on Induced Labor Effects of Pregnant Women with Scarred Uterus in Second Trimester

作　　者：王玉美[1] WANG Yumei(Department of Obstetrics,Ward 2,Qufu People's Hospital,Qufu 273100,China)

机构地区：[1]曲阜市人民医院产科二区,山东曲阜273100

出　　处：《反射疗法与康复医学》2024年第24期100-102,106,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨妊娠中期瘢痕子宫引产孕妇应用米非司酮与乳酸依沙吖啶联合子宫颈扩张球囊引产的效果。方法回顾性分析2019年6月—2024年5月于曲阜市人民医院进行引产的70例妊娠中期瘢痕子宫孕妇的临床资料,根据引产方案的不同将其分为对照组和观察组,每组35例。对照组采用乳酸依沙吖啶与米非司酮引产,观察组在对照组的基础上采用子宫颈扩张球囊引产。比较两组患者的引产效果、引产后不同分娩阶段引产成功率、疼痛等级及并发症发生情况。结果观察组引产时间短于对照组,产后出血量少于对照组,组间差异有统计学意义(P<0.05);观察组引产后0~24 h引产成功率高于对照组,48~72 h引产成功率低于对照组,组间差异有统计学意义(P<0.05);两组引产后24~48 h引产成功率比较,差异无统计学意义(P>0.05);观察组疼痛等级分级优于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为8.57%,低于对照组的40.00%,差异有统计学意义(P<0.05)。结论妊娠中期瘢痕子宫孕妇采用米非司酮与乳酸依沙吖啶联合子宫颈扩张球囊引产,可显著提升引产成功率,缓解疼痛程度,且安全性较高,并发症较少。Objective To explore the effect of mifepristone and ethacridine lactate combined with cervical dilatation balloon in induced labor of pregnant women with scarred uterus in second trimester.Methods Clinical data of 70 pregnant women with scar uterus who underwent labor induction in Qufu People's Hospital from June 2019 to May 2024 were retrospectively analyzed,and they were divided into a control group and an observation group according to different labor induction programs,with 35 cases in each group.The control group was induced by ethacridine lactate and mifepristone,and the observation group was induced by cervical dilation balloon on the basis of the control group.The induced labor effects,the success rate of induction of labor in different stages of labor,pain grade and occurrence of complications were compared between the two groups.Results The time of labor induction in the observation group was shorter than that in the control group,and the amount of postpartum blood loss was less than that in the control group,the differences between the groups were statistically significant(P<0.05);the success rate of induction 0 to 24 hours in the observation group was higher than that in the control group,and the success rate of induction 48 to 72 hours was lower than that in the control group,the differences between the groups were statistically significant(P<0.05);there was no significant difference in the success rate of induction 24 to 48 hours after induction between the two groups(P>0.05).The pain grade of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05);the complication rate of the observation group was 8.57%,which was lower than 40.00%of the control group,and the difference was statistically significant(P<0.05).Conclusion The mifepristone and ethacridine lactate combined with cervical dilation balloon can significantly improve the success rate of labor induction,relieve the degree of pain,and have higher safety and fewer complications for

关 键 词：瘢痕子宫 妊娠中期 米非司酮 乳酸依沙吖啶 子宫颈扩张球囊 

分 类 号：R714[医药卫生—妇产科学]