射频消融治疗气管旁Bethesda Ⅴ及Ⅵ类甲状腺结节的临床研究  

Clinical Study of Radiofrequency Ablation for Paratracheal Bethesda Ⅴ and Ⅵ Thyroid Nodule

作　　者：杨旭芬 王一帆 常莹[1] 杨敬春[1] Yang Xufen;Wang Yifan;Chang Ying;Yang Jingchun(Department of Ultrasound Diagnosis,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院超声诊断科,北京市100053

出　　处：《中国超声医学杂志》2025年第2期125-128,共4页Chinese Journal of Ultrasound in Medicine

基　　金：首都医科大学临床专科学院(系)培养基金(No.CCMU2023ZKYXY022)。

摘　　要：目的探讨超声引导下射频消融治疗气管旁Bethesda Ⅴ及Ⅵ类低危甲状腺结节的有效性及安全性。方法回顾性分析射频消融治疗的144例Bethesda Ⅴ及Ⅵ类低危甲状腺结节,按病灶位置分为邻近气管组与非邻近气管组,评估术前基线情况及术后病灶吸收率和疾病进展情况。结果共144例甲状腺消融病灶,术前基线资料差异无统计学意义,术后邻近气管组病灶吸收率高于对照组(P<0.05),病灶累积消失率较对照组升高1.8倍(HR=2.8,95%CI:1.46~5.37,P=0.002),两组间疾病进展差异无统计学意义,采用多因素Cox回归显示邻近气管与疾病进展无相关性(HR=0.85,95%CI:0.09~8.40,P=0.886)。结论超声引导下射频消融治疗气管旁低危Bethesda Ⅴ及Ⅵ类甲状腺结节具有一定的有效性及安全性。Objective To investigate the efficacy and safety of ultrasound-guided radiofrequency ablation in the treatment of paratracheal Bethesda Ⅴ and Ⅵ low risk with thyroid nodule.Methods A total of 144 cases of Bethesda Ⅴ and Ⅵ low risk thyroid nodule treated by radiofrequency ablation were retrospectively analyzed.According to the location of the lesions,they were divided into adjacent trachea group and non-adjacent trachea group,and the preoperative baseline situation,postoperative lesion absorption rate and disease progression were evaluated.Results There were 144 cases of thyroid ablation lesions,and there was no statistical difference in preoperative baseline data.The absorption rate of lesions in the adjacent trachea group was higher than that in the control group(P<0.05),and the cumulative disappearance rate of lesions increased by 1.8 times compared with the control group(HR=2.8,95%CI:1.46-5.37,P=0.002).There was no statistical difference in disease progression between the two groups.Multivariate Cox regression showed that there was no correlation between the adjacent trachea and disease progression(HR=0.85,95%CI:0.09-8.40,P=0.886).Conclusions Ultrasound-guided radiofrequency ablation has certain efficacy and safety in the treatment of paratracheal low risk Bethesda Ⅴ and Ⅵ thyroid nodule.

关 键 词：气管 甲状腺结节 射频消融 

分 类 号：R73[医药卫生—肿瘤]