小肠细菌过度生长与功能性胃肠病关系的研究进展  

Progress on the relationship between small intestinal bacterial overgrowth and functional gastrointestinal disorders

作　　者：符晓莉[1] 魏绪霞[1] 徐俊杰[1] 陈红苓 张乐[1] 薛宁[1] Fu Xiaoli;Wei Xuxia;Xu Junjie;Chen Hongling;Zhang Le;Xue Ning(Department of Gastroenterology,Children's Hospital Affiliated to Shandong University(Jinan Children's Hospital),Jinan 250022,China)

机构地区：[1]山东大学附属儿童医院(济南市儿童医院)消化科,250022

出　　处：《国际儿科学杂志》2025年第1期27-32,共6页International Journal of Pediatrics

基　　金：济南市卫生健康委员会科技计划项目(2024304014)。

摘　　要：小肠细菌过度生长(small intestinal bacterial overgrowth,SIBO)是一种临床常见但未被充分认识的疾病,其临床症状与功能性胃肠病(functional gastrointestinal disorders,FGID)的症状重叠。FGID是SIBO发生的常见危险因素,其SIBO发病率明显高于健康人群,且呈一定相关性。肠道微生态失调(包括SIBO)在FGID的病理生理学机制中起重要作用。目前SIBO的诊断与治疗仍具有挑战性,FGID的治疗方案被逐步引入SIBO的治疗。SIBO与FGID在临床表现、发病率、病理生理、治疗等方面均存在密切联系,但关于两者之间关系研究较少,需前瞻性的、大规模的临床研究以提高对两者的认识及诊断准确率。该文就SIBO与FGID关系的研究进展进行综述。Small intestinal bacterial overgrowth(SIBO)is a clinically common but poorly recognized disease with clinical symptoms that overlap with those of functional gastrointestinal disorders(FGID).FGID is a common risk factor for the occurrence of SIBO,and its SIBO incidence rate is significantly higher than that of healthy people,and has a certain correlation.Intestinal microbiota dysbiosis(including SIBO)plays an important role in the pathophysiology of FGID.At present,the diagnosis and treatment of SIBO still face challenges,and the treatment plan of FGID is gradually introduced into the treatment of SIBO.SIBO and FGID are closely related in clinical manifestations,incidence rate,pathophysiology,treatment and other aspects,but there is little research on the relationship between them.Prospective and large-scale clinical research is still needed to improve understanding and diagnostic accuracy.This article reviews the research progress on the relationship between SIBO and FGID.

关 键 词：小肠细菌过度生长 功能性胃肠病 病理生理学 诊断 治疗 

分 类 号：R57[医药卫生—消化系统]