Construction of a 12-metal Zn(Ⅱ)-Nd(Ⅲ) nanocluster for ratiometric fluorescence detection of inflammatory marker neopterin  

作　　者：Huanyin Yu Xiaoping Yang Xiaoli Lv Xianfeng Huang 

机构地区：[1]College of Chemistry and Materials Engineering,Wenzhou University,Zhejiang Key Laboratory of Carbon Materials,Key Lab of Biohealth Materials and Chemistry of Wenzhou,Wenzhou,325035,China

出　　处：《Journal of Rare Earths》2025年第2期270-275,I0002,共7页稀土学报(英文版)

基　　金：Project supported by the National Natural Science Foundation of China (21771141)。

摘　　要：A 12-metal Zn(Ⅱ)-Nd(Ⅲ) cluster 1(sizes:1.8 nm×2.0 nm×2.0 nm) was synthesized from a long-chain type Schiff base ligand.It displays ratiometric fluorescence response to neopterin(Neo) with high selectivity and sensitivity,which can be expressed by the equation I_(545)_(nm)/I_(1060)_(nm)=A·[Neo]^(2)+B·[Neo]+C.1 is used to quantitatively test Neo concentrations in fetal calf serum(FCS) and urine,and the recovery ranges are 98.57%-103.82% and 99.25%-103.50%,respectively,while the relative standard deviations(RSDs) are 7.89%-9.46% and 1.85%-4.16%,respectively.The limits of detection of 1 to Neo in FCS and urine are 0.034 and 0.021 μmol/L,respectively.

关 键 词：Rare earths Zn(Ⅱ)-Nd(Ⅲ)nanocluster NIR luminescence Ratiometric fluorescence detection NEOPTERIN 

分 类 号：R73[医药卫生—肿瘤]