腹腔镜下行胃穿孔修补术对急性胃溃疡穿孔患者的治疗效果分析  

Effect Analysis of Laparoscopically Gastric Perforation Repair in Patients with Acute Gastric Ulcer Perforation

作　　者：荣瑜 RONG Yu(Department of General Surgery,Zibo Municipal Hospital,Zibo 255000,China)

机构地区：[1]山东省淄博市市立医院普外科,山东淄博255000

出　　处：《中国伤残医学》2024年第22期35-38,47,共5页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:探讨腹腔镜下行胃穿孔修补术对急性胃溃疡穿孔患者的治疗效果。方法:回顾性分析2015年3月-2024年2月淄博市市立医院收治的61例急性胃溃疡穿孔患者的临床资料,按照手术方法的不同将其分为对照组(n=30)和研究组(n=31)。对照组采用传统开腹穿孔修补术,研究组采用腹腔镜下胃穿孔修补术。两组均观察至术后2 d。比较两组临床相关指标、应激反应指标、胃蛋白酶原及并发症发生情况。结果:研究组手术时间、住院时间、引流管拔管时间均短于对照组,术中出血量少于对照组,差异均有统计学意义(P<0.05)。术后2 d,研究组肿瘤坏死因子-α、白介素-6、C反应蛋白的指标水平均低于对照组,差异均有统计学意义(P<0.05)。术后2 d,研究组胃蛋白酶原-Ⅰ、胃蛋白酶原-Ⅱ均低于对照组,差异均有统计学意义(P<0.05)。研究组的并发症发生率为3.23%,低于对照组的26.57%,差异有统计学意义(P<0.05)。结论:急性胃溃疡穿孔患者采用腹腔镜下行胃穿孔修补术能够改善临床相关指标及胃蛋白酶原指标,降低应激反应指标,且并发症发生率更低,有利于患者术后恢复。Objective:To investigate the therapeutic effect of laparoscopically gastric perforation repair in patients with acute gastric ulcer perforation.Methods:The clinical data of 61 patients with acute gastric ulcer perforation admitted to Zibo Municipal Hospital from March 2015 to February 2024 were retrospectively analyzed,and they were divided into a control group(n=30)and a study group(n=31)according to different surgical methods.The control group underwent traditional open perforation repair surgery,while the study group underwent laparoscopically gastric perforation repair surgery.Both groups were observed until 2 days after surgery.The clinical related indicators,stress response indicators,pepsinogen,and the occurrence of complications were compared between the two groups.Results:The operation time,hospital stay,and drainage tube removal time of the study group were shorter than those of the control group;the intraoperative blood loss of the study group was less than that of the control group,the differences were statistically significant(P<0.05).Two days after surgery,the levels of tumor necrosis factor-α,interleukin-6 and C-reactive protein in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).Two days after surgery,the levels of pepsinogenⅠand pepsinogenⅡin the study group were lower than those in the control group,with statistical significance(P<0.05).The incidence of complications in the study group was 3.23%,which was lower than 26.57%in the control group,the difference was statistically significant(P<0.05).Conclusion:Laparoscopically gastric perforation repair in patients with acute gastric ulcer perforation can improve clinical and pepsinogen indexes,reduce stress response indexes,and lower the incidence of complications,which is conducive to postoperative recovery of patients.

关 键 词：胃溃疡穿孔 腹腔镜 胃穿孔修补术 胃蛋白酶原 

分 类 号：R62[医药卫生—整形外科]