益气通脉汤加减治疗对气虚血瘀型急性心肌梗死患者中医证候积分及心功能指标的影响  

Effect of Yiqi Tongmai Decoction with Modifications on Traditional Chinese Medicine Syndrome Score and Cardiac Function Indicators in Patients with Acute Myocardial Infarction with Qi Deficiency and Blood Stasis Type

作　　者：曲芳 QU Fang(Department of Cardiology,Yantai Penglai Hospital of Traditional Chinese Medicine,Yantai 265600,China)

机构地区：[1]烟台市蓬莱中医医院心病一科,山东烟台265600

出　　处：《反射疗法与康复医学》2024年第23期28-31,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨益气通脉汤加减治疗气虚血瘀型急性心肌梗死(AMI)患者的疗效。方法选择烟台市蓬莱中医医院2021年4月—2022年12月收治的98例气虚血瘀型AMI患者为研究对象,按随机数字表法将其分为对照组和观察组,各49例。对照组采用常规静脉溶栓治疗,观察组在对照组基础上联合益气通脉汤加减治疗,两组均持续治疗8周。对比两组的中医证候积分、心功能指标、生活质量及心血管不良事件(MACE)的发生情况。结果治疗后,观察组各项中医证候积分均低于对照组,组间差异有统计学意义(P<0.05);观察组左心室射血分数高于对照组,心排血量、每搏输出量均多于对照组,左室舒张末期内径、左室收缩末期内径均短于对照组,组间差异有统计学意义(P<0.05);观察组西雅图心绞痛量表评分高于对照组,差异有统计学意义(P<0.05)。观察组MACE发生率为16.33%,低于对照组的2.04%,差异有统计学意义(P<0.05)。结论益气通脉汤加减治疗气虚血瘀型AMI患者可缓解临床症状,改善心功能,提升生活质量,减少MACE的发生。Objective To explore the therapeutic effect of Yiqi Tongmai decoction with modifications on acute myocardial infarction(AMI)with Qi deficiency and blood stasis type.Methods A total of 98 patients with AMI of Qi deficiency and blood stasis type admitted to Yantai Penglai Hospital of Traditional Chinese Medicine from April 2021 to December 2022 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 49 cases in each group.The control group was treated with conventional intravenous thrombolysis,and the observation group was treated with Yiqi Tongmai decoction with modifications on the basis of control group,both groups were treated for 8 weeks.Traditional Chinese Medicine syndrome score,cardiac function indicators,quality of life and occurrence of major adverse cardiovascular events(MACE)were compared between the two groups.Results After treatment,the scores of Traditional Chinese Medicine syndrome in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05);left ventricular ejection fraction was higher than that in the control group,cardiac output and stroke output in the observation group were more than those in the control group,and left ventricular end-diastolic diameter and left ventricular end-systolic diameter were shorter than those in the control group,and the differences between the groups were statistical significance(P<0.05);the Seattle Angina Questionnaire score of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The incidence of MACE in the observation group was 16.33%,which was lower than 2.04%in the control group,and the difference was statistically significant(P<0.05).Conclusion Yiqi Tongmai decoction with modifications can relieve clinical symptoms,improve heart function,enhance quality of life and reduce MACE occurrence in patients with AMI with Qi defici

关 键 词：急性心肌梗死 气虚血瘀型 益气通脉汤加减 中医证候 心功能 不良心血管事件 

分 类 号：R542[医药卫生—心血管疾病]