机构地区:[1]北京大学公共卫生学院社会医学与健康教育系,北京100191 [2]郑州大学附属传染病医院(河南省传染病医院)感染科 [3]墨尔本大学
出 处:《医学动物防制》2025年第3期246-253,共8页Journal of Medical Pest Control
基 金:河南省传染病(艾滋病)临床医学研究中心开放课题资助项目(KFKT202409);陕西省自然科学基础研究计划项目(2022JM-592)。
摘 要:目的探讨全球范围内艾滋病与冠心病关联性研究的发展态势和前沿焦点,为制定我国艾滋病患者防治冠心病的政策措施和两种疾病关联性的深入研究提供依据。方法检索1993年1月—2024年3月Web of Science Core Collection(WoSCC)数据库中艾滋病与冠心病关联性的相关文章,导入EndNote X9进行文献去重和管理,用Citespace 6.2.R4等绘制国家、作者合作网络图谱和关键词共现、聚类及突现展示。结果共纳入1147篇文献。发文数量最多的期刊和国家分别是《艾滋病》(AIDS)和美国,发文数量排名前10的研究机构均属美国。研究主题主要集中在心血管疾病(cardiovascular diseases)等方面。聚类分析形成13类,研究总结为HIV感染者已经或可能发生的心血管疾病、自身HIV的研究和再患冠心病的特异性风险因素研究三大类。突现词分析表明亚临床动脉粥样硬化(subclinical atherosclerosis)等是未来几年的研究热点。结论未来全球80%以上的艾滋病患者存在亚临床动脉粥样硬化的发病趋势,我国艾滋病患者众多,艾滋病与冠心病关联性研究较薄弱。在今后的研究中可结合我国国情进一步挖掘,以提高艾滋病群体的生命质量,减轻疾病负担。Objective To investigate the global research trends and frontiers focus in the association between AIDS and coronary heart disease,providing a foundation for the development of policy measures for the prevention and treatment of coronary heart disease among AIDS patients in China,as well as for further in-depth research into the link between the two diseases.Methods A literature search was conducted for articles related to the association between AIDS and coronary heart disease in the Web of Science Core Collection(WoSCC)database from January 1993 to March 2024.The articles were deduplicated and managed using EndNote X9,and visualizations of country and author collaboration networks,keyword co-occurrence,clustering,and burst detection were created using Citespace 6.2.R4 etcetera.Results A total of 1147 literatures were included.The journal and countries with the highest number of publications was AIDS,and the United States respectively.All of the top 10 research institutions by publication volume were based in the United States.The primary research themes centered on cardiovascular diseases among others.Cluster analysis identified 13 distinct categories,with the research synthesizing into three main areas:cardiovascular diseases that had occurred or were likely to occur in HIV-infected individuals,research on the HIV itself,and studies on the specific risk factors for coronary heart disease recurrence.The analysis of burst terms indicates that subclinical atherosclerosis etcetera were poised to become a significant research focus in the coming years.Conclusion It is projected that over 80%of global AIDS patients will exhibit incidence trends of subclinical atherosclerosis in the future.Given the substantial number of AIDS patients in China and the relatively weak research on the association between AIDS and coronary heart disease,future studies should integrate China′s national context to enhance the quality of life for the AIDS population and alleviate the disease burden.
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