2013—2022年南通市丙型病毒性肝炎流行特征分析  

Epidemiological characteristic analysis of viral hepatitis type C in Nantong City from 2013 to 2022

作　　者：周小毅[1] 刘凯 朱平[1] 夏宏丽[1] 章施静 马平[1] ZHOU Xiaoyi;LIU Kai;ZHU Ping;XIA Hongli;ZHANG Shijing;MA Ping(STD/AIDS Prevention and Control Department,Nantong Center for Disease Control and Prevention,Nantong,Jiangsu 226007,China)

机构地区：[1]南通市疾病预防控制中心性病艾滋病防制科,江苏南通226007

出　　处：《医学动物防制》2025年第2期114-118,123,共6页Journal of Medical Pest Control

基　　金：国家科技部重点研发项目(2022YFC2304901);江苏省卫健委预防医学科研课题面上项目(Ym2023079);南通市卫生健康委员会科研立项课题(MB2021075);南通市卫健委“十四五”科教强卫工程青年医学重点人才项目(通卫科教[2021]15号);南通市卫健委“十四五”科教强卫工程医学重点学科(传染病学)项目(通卫科教[2021]15号)。

摘　　要：目的了解2013—2022年江苏省南通市丙型病毒性肝炎(简称丙肝)的流行特征,为丙肝防控提供科学依据。方法收集并整理南通市2013—2022年丙肝病例数据,下载人口学数据,应用描述性流行病学方法,用占比对分类变量进行描述,采用χ^(2)检验进行组间比较。结果2013—2022年南通市累计报告丙肝病例1519例,年均报告发病率为1.97/10万,发病率总体呈上升趋势(χ^(2)=108.761,P<0.001)。丙肝病例以确诊病例为主(占90.19%),病例分类以慢性为主(占85.12%)。男性年均发病率为2.11/10万,女性年均发病率为1.83/10万,男女性丙肝报告发病率性别比为0.86∶1~2.03∶1,平均为1.12∶1,65~<70岁年龄组报告发病率最高(0.83/10万~5.59/10万,年均发病率为4.04/10万),55~<60岁年龄组报告发病率增长幅度最大。丙肝报告病例的职业分布以农民为主,共报告964例(63.46%),其次为家务及待业人员182例(11.98%)和离退人员182例(11.98%)。如皋市丙肝年均报告发病率最高,为3.85/10万,通州区最低,为0.69/10万。结论2013—2022年南通市丙肝发病率呈上升趋势,存在明显的地区差异。50岁以上老年人发病例数多,发病率增长幅度大,应加强对重点地区、重点人群的病例筛查和宣传教育。Objective To understand the epidemiological characteristics of viral hepatitis type C(referred to as hepatitis C)in Nantong City,Jiangsu Province from 2013 to 2022,so as to provide scientific basis for the prevention and control of hepatitis C.Methods Data of hepatitis C cases in Nantong City from 2013 to 2022 were collected and sorted out,and demographic data were downloaded.Using descriptive epidemiology method,the classification variables of percentage were used for description,and inter-group comparison was conducted byχ^(2)test.Results A total of 1519 cases of hepatitis C were cumulative reported in Nantong City from 2013 to 2022,with an average annual reported incidence rate of 1.97/100000,and the incidence rate showed an overall increasing trend(χ^(2)=108.761,P<0.001).The majority of hepatitis C cases were predominantly confirmed cases(90.19%),and classification of cases was predominantly chronic(85.12%).The average annual incidence rate was 2.11/100000 in males and 1.83/100000 in females.The sex ratio of reported incidence rates of hepatitis C between males and females was 0.86∶1-2.03∶1,with an average of 1.12∶1.The 65-<70 years age group the highest reported incidence rate(0.83/100000 to 5.59/100000,with an average annual incidence rate of 404/100000).The age group of 55-<60 years had the greatest increase in reported incidence rate.The occupational distribution of hepatitis C cases was mainly farmers,a total of 964 cases were reported(63.46%),followed by 182 cases(11.98%)of housework and waiting for work and 182 cases(11.98%)of retirees.The average annual reported incidence rate was highest as 3.85/100000 in Rugao City and lowest as 0.69/100000 in Tongzhou District.Conclusion The incidence rate of hepatitis C in Nantong City from 2013 to 2022 shows an increasing trend,with obvious regional differences.The number of cases in elderly people over 50 years old is large,and the incidence rate increases greatly.Case screening and publicity and education should be strengthened in key areas and key popu

关 键 词：HCV 丙型病毒性肝炎 流行特征 发病率 流行趋势 疾病控制 分析 

分 类 号：R512.63[医药卫生—内科学]