急性胰腺炎与肠道菌群相关性的研究进展  

Research Progress in the Correlation between Acute Pancreatitis and Intestinal Flora

作　　者：胡柳慧 黄夏冰[2] HU Liuhui;HUANG Xiabing(Guangxi University of Chinese Medicine,Nanning 530000,China;Department of Emergency Medicine,the First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530000,China)

机构地区：[1]广西中医药大学,广西南宁530000 [2]广西中医药大学第一附属医院急诊科,广西南宁530000

出　　处：《基层中医药》2025年第1期89-95,共7页Basic Traditional Chinese Medicine

摘　　要：急性胰腺炎(AP)易导致全身炎症反应综合征和多器官功能障碍综合征。急性肺损伤是AP最严重的并发症之一。许多研究发现,肠道菌群与AP的进展、并发症的产生有着密切的关系。中医将AP归属为“腹痛”“胃心痛”“脾心痛”“胰瘅”等范畴,研究发现,一些中药单药、方剂对调节AP肠道菌群具有一定的优势,肠道菌群与AP的相关性研究给AP的治疗方案提供了新思路。笔者通过检索PubMed及中国知网(CNKI)近十年AP与肠道菌群相关性研究文章,对其中的观点和治疗方法进行整理,旨在为AP的治疗提供参考。Acute pancreatitis(AP)may induce systemic inflammatory response syndrome and multiple organ dysfunction syndrome.Acute lung injury is one of the most serious complications of AP.Studies have shown that intestinal flora is associated with the progression of AP and the development of complications.In traditional Chinese medicine(TCM),AP is classified as abdominal pain,gastric pain,precordial pain due to spleen disorder,and pancreatic fever.Some single Chinese medicines and TCM compound prescriptions have advantages in regulating the intestinal flora of AP patients.The study of the correlation between intestinal flora and AP provides new ideas for the treatment of AP.We searched PubMed and CNKI for the articles involving the correlation between AP and intestinal flora that were published in the past ten years and sorted out the opinions and therapies therein,aiming to provide a reference for the treatment of AP.

关 键 词：肠道菌群 急性胰腺炎 菌群-肠-肺轴 综述 

分 类 号：R47[医药卫生—护理学]