某医院胃癌根治术患者手术部位感染危险因素分析  

Analysis of risk factors for surgical site infection in patients undergoing radical gastrectomy for gastric cancer in a hospital

作　　者：罗进 张书勤 燕速[2] 邢多 施昊旻 杨惠莲[1] LUO Jin;ZHANG Shu-qin;YAN Su;XING Duo;SHI Hao-min;YANG Hui-lian(Qinghai University School of Medicine,Xining 810001,China;Qinghai University Affiliated Hospital)

机构地区：[1]青海大学医学部,青海西宁810001 [2]青海大学附属医院

出　　处：《中国消毒学杂志》2025年第1期42-45,共4页Chinese Journal of Disinfection

摘　　要：目的研究胃癌根治术后手术部位感染的危险因素及病原菌分布。方法通过医院感染监测和病原菌分离鉴定技术,对某医院行胃癌根治术患者术后切口感染及病原菌分布情况进行观察和分析。结果在纳入研究的1451例胃癌根治术患者中,发生手术部位感染202例,感染率为13.92%。多因素分析结果显示,患者年龄、脉管侵犯、手术时间、全胃切除和引流管数等构成术后切口感染的独立危险因素(P<0.05)。从202例术后切口感染患者送检标本中,共检出病原菌135株,革兰阴性菌占54.06%,主要为肺炎克雷伯菌、铜绿假单胞菌和大肠埃希菌,构成比依次为8.15%、7.41%和23.70%。结论该医院胃癌根治术患者手术部位感染率较高,危险因素为高龄、脉管侵犯、较长手术时间、放置较多引流管,感染的病原菌以革兰阴性菌为主。Objective To investigate the risk factors and pathogen distribution of surgical site infection after radical gastrectomy for gastric cancer.Methods Through nosocomial infection monitoring and pathogen isolation and identification techniques,the postoperative incision infection and pathogen distribution of patients undergoing radical gastrectomy in a hospital were observed and analyzed.Results Among the 1451 included patients who underwent radical gastrectomy for gastric cancer in the study,202 cases occurred surgical site infection,with an infection rate of 13.92%.The results of multivariate analysis showed that patient age,vascular invasion,surgical time,total gastrectomy,and number of drainage tubes were independent risk factors for postoperative incision infection.A total of 135 strains of pathogenic bacteria were detected from 202 patients with postoperative incision infection,and gram-negative bacteria accounted for 54.06%and the main pathogens were Klebsiella pneumoniae,Pseudomonas aeruginosa,and Escherichia coli,accounting for 8.15%,7.41%,and 23.70%,respectively.Conclusion The rate of surgical site infection in patients undergoing radical gastrectomy in this hospital is relatively high,and the risk factors may include advanced age,vascular invasion,longer surgical time,and placement of more drainage tubes.The main pathogenic bacteria causing infection are gram-negative bacteria.

关 键 词：胃癌根治术 手术部位感染 危险因素 病原菌 多因素分析 

分 类 号：R181.32[医药卫生—流行病学]